Literature DB >> 12722152

Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats.

P Stanely Mainzen Prince1, Venugopal P Menon.   

Abstract

The present investigation was undertaken to evaluate the hypoglycaemic and hypolipidaemic effects of an alcohol extract of Tinospora cordifolia roots, an indigenous plant used in Ayurvedic medicine in India. Oral administration of the extract of Tinospora cordifolia (TCREt) roots for 6 weeks resulted in a significant reduction in blood and urine glucose and in lipids in serum and tissues in alloxan diabetic rats. The extract also prevented a decrease in body weight. Thus our study clearly shows that an alcohol TCREt has a hypoglycaemic and hypolipidaemic action. Copyright 2003 John Wiley & Sons, Ltd.

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Year:  2003        PMID： 12722152     DOI： 10.1002/ptr.1130

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  11 in total

1.  Hypoglycemic, lipid lowering and antioxidant activities in root extract of Anthocephalus indicus in alloxan induced diabetic rats.

Authors:  Vishnu Kumar; A K Khanna; M M Khan; Ranjana Singh; Sushma Singh; Ramesh Chander; Farzana Mahdi; J K Saxena; Shweta Saxena; V K Singh; R K Singh
Journal:  Indian J Clin Biochem       Date:  2009-05-08

Review 2.  Nanotechnological approaches for the development of herbal drugs in treatment of diabetes mellitus - a critical review.

Authors:  Saritha Marella; Naga Venkata Krishna Vara Prasad Tollamadugu
Journal:  IET Nanobiotechnol       Date:  2018-08       Impact factor: 1.847

3.  Evidences for the Involvement of Monoaminergic and GABAergic Systems in Antidepressant-like Activity of Tinospora cordifolia in Mice.

Authors:  D Dhingra; P K Goyal
Journal:  Indian J Pharm Sci       Date:  2008-11       Impact factor: 0.975

4.  Double-blind, placebo-controlled clinical evaluation of an Ayurvedic formulation (GlucoCare capsules) in non-insulin dependent diabetes mellitus.

Authors:  R K Sharma; Pralhad S Patki
Journal:  J Ayurveda Integr Med       Date:  2010-01

5.  Effect of aqueous extract of Tinospora cordifolia on functions of peritoneal macrophages isolated from CCl4 intoxicated male albino mice.

Authors:  Mahuya Sengupta; Gauri D Sharma; Biswajit Chakraborty
Journal:  BMC Complement Altern Med       Date:  2011-10-28       Impact factor: 3.659

6.  A pharmacological appraisal of medicinal plants with antidiabetic potential.

Authors:  Vasim Khan; Abul Kalam Najmi; Mohd Akhtar; Mohd Aqil; Mohd Mujeeb; K K Pillai
Journal:  J Pharm Bioallied Sci       Date:  2012-01

7.  Indian herbs and herbal drugs used for the treatment of diabetes.

Authors:  Manisha Modak; Priyanjali Dixit; Jayant Londhe; Saroj Ghaskadbi; Thomas Paul A Devasagayam
Journal:  J Clin Biochem Nutr       Date:  2007-05       Impact factor: 3.114

Review 8.  The chemical constituents and diverse pharmacological importance of Tinospora cordifolia.

Authors:  Priyanka Sharma; Bharat P Dwivedee; Dheeraj Bisht; Ashutosh K Dash; Deepak Kumar
Journal:  Heliyon       Date:  2019-09-12

9.  Tinospora cordifolia: One plant, many roles.

Authors:  Soham Saha; Shyamasree Ghosh
Journal:  Anc Sci Life       Date:  2012-04

10.  Comparative Therapeutic Effects of Plant-Extract Synthesized and Traditionally Synthesized Gold Nanoparticles on Alcohol-Induced Inflammatory Activity in SH-SY5Y Cells In Vitro.

Authors:  Ashok K Singh
Journal:  Biomedicines       Date:  2017-12-15
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