| Literature DB >> 12722145 |
S E Besra1, A Gomes, D K Ganguly, J R Vedasiromoni.
Abstract
The effect of a hot water extract of black tea (Camellia sinensis (L.) O. Kuntze, Theaceae) on upper gastrointestinal transit and on diarrhoea was investigated employing conventional rodent models of diarrhoea. Black tea extract was found to possess antidiarrhoeal activity in all the models of diarrhoea used. Naloxone (0.5 mg/kg i.p.) significantly inhibited the antidiarrhoeal activity of the extract as well as loperamide, thus indicating a role of the opioid system in the antidiarrhoeal activity of the extract. Copyright 2003 John Wiley & Sons, Ltd.Entities:
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Year: 2003 PMID: 12722145 DOI: 10.1002/ptr.1171
Source DB: PubMed Journal: Phytother Res ISSN: 0951-418X Impact factor: 5.878