| Literature DB >> 1271978 |
J C Montet, A M Montet, A Gerolami, J Amic, J C Hauton.
Abstract
Glycodihydrofusidate, which has the same detergent properties a bile salts, is excreted almost exclusively by the bile duct after intravenous injection in the rat. As with bile salts, it leads to a significant (P less tthan or equal to 0.05) increase in excretion of lecithins and cholesterol (0.15 mumol lecithin and 0.026 mumol cholesterol per 1 mumol of glycodihydrofusidate excreted). In addition, this drug simulataneously inhibits excretion of both endogenous bile salts and bile pigments.Entities:
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Year: 1976 PMID: 1271978 DOI: 10.1007/BF02532848
Source DB: PubMed Journal: Lipids ISSN: 0024-4201 Impact factor: 1.880