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Literature DB >> 12715872

YM-266183 and YM-266184, novel thiopeptide antibiotics produced by Bacillus cereus isolated from a marine sponge II. Structure elucidation.

Ken-ichi Suzumura¹, Takako Yokoi, Masashi Funatsu, Koji Nagai, Koichi Tanaka, Huiping Zhang, Kenichi Suzuki.

Abstract

YM-266183 and YM-266184 are new antibacterial substances that have activity against drug-resistant bacteria produced by Bacillus cereus QN03323. These structures were elucidated by MS and NMR spectral analysis. YM-266183 and YM-266184 are the cyclic thiopeptides containing thiazole and pyridine moieties, and several unusual amino acids.

Entities: Chemical Species

Mesh：

Substances：

Year: 2003 PMID： 12715872 DOI： 10.7164/antibiotics.56.129

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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Cited

12 in total

Review 1. Development of antibiotics and the future of marine microorganisms to stem the tide of antibiotic resistance.

Authors: Noer Kasanah; Mark T Hamann
Journal: Curr Opin Investig Drugs Date: 2004-08

2. Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.

Authors: Laura C Wieland Brown; Michael G Acker; Jon Clardy; Christopher T Walsh; Michael A Fischbach
Journal: Proc Natl Acad Sci U S A Date: 2009-02-05 Impact factor: 11.205

3. In vitro antiplasmodial activity of bacterium RJAUTHB 14 associated with marine sponge Haliclona Grant against Plasmodium falciparum.

Authors: Samuel Jacob Inbaneson; Sundaram Ravikumar
Journal: Parasitol Res Date: 2011-12-23 Impact factor: 2.289

Review 4. Antibacterials from the sea.

Authors: Chambers C Hughes; William Fenical
Journal: Chemistry Date: 2010-11-08 Impact factor: 5.236

YM-266183 and YM-266184, novel thiopeptide antibiotics produced by Bacillus cereus isolated from a marine sponge II. Structure elucidation.

Review 1. Development of antibiotics and the future of marine microorganisms to stem the tide of antibiotic resistance.

2. Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.

3. In vitro antiplasmodial activity of bacterium RJAUTHB 14 associated with marine sponge Haliclona Grant against Plasmodium falciparum.

Review 4. Antibacterials from the sea.

Review 5. Marine drugs from sponge-microbe association--a review.

Review 6. Bioprospecting Sponge-Associated Microbes for Antimicrobial Compounds.

Review 7. YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.

8. Antibacterial activity of halophilic bacterial bionts from marine invertebrates of mandapam-India.

Review 9. α,β-Dehydroamino acids in naturally occurring peptides.

Review 10. Nonribosomal Peptides from Marine Microbes and Their Antimicrobial and Anticancer Potential.