| Literature DB >> 1271520 |
I M Kerr, U Olshevsky, H F Lodish, D Baltimore.
Abstract
The virion RNA of Moloney murine leukemia virus (MuLV) has been translated in eukaryotic cell-free systems derived from mouse L- and human HeLa cells. In both systems at least three polypeptides, approximately 60,000, 70,000, and 180,000 in apparent molecular weight, were formed in response to the added 35S MuLV RNA. All three polypeptides were precipitable with antiserum to detergent-disrupted MuLV. Fingerprint analysis of tryptic digests indicated that all three contain anino acid sequences in common with each other and with the major methionine-containing structural proteins of the virion.Entities:
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Year: 1976 PMID: 1271520 PMCID: PMC515589 DOI: 10.1128/JVI.18.2.627-635.1976
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103