Literature DB >> 12713588

p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta.

Richard L Eckert1, Tatiana Efimova, Sivaprakasam Balasubramanian, James F Crish, Frederic Bone, Shervin Dashti.   

Abstract

The p38 family of mitogen-activated protein kinases includes p38 alpha (SAPK2a, CSBP), p38 beta (SAPK2b), p38 delta (SAPK4), and p38 gamma (SAPK3/ERK6). p38 alpha and p38 beta are widely expressed p38 isoforms that are involved in regulation of cell proliferation, differentiation, development, and response to stress. Relatively less is known regarding the function of the p38 delta isoform. In this review, we discuss the role of the p38 alpha, p38 beta, and p38 gamma isoforms and then present recent findings that define a role for p38 delta as a regulator of differentiation-dependent gene expression in keratinocytes.

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Year:  2003        PMID： 12713588     DOI： 10.1046/j.1523-1747.2003.12120.x

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  31 in total

1.  Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes.

Authors:  Shuko Okada; Akihiko Muto; Eisaku Ogawa; Ayako Nakanome; Yasutake Katoh; Shuntaro Ikawa; Setsuya Aiba; Kazuhiko Igarashi; Ryuhei Okuyama
Journal:  J Biol Chem       Date:  2010-05-25       Impact factor: 5.157

2.  Activation of Cdc2 contributes to apoptosis in HPV E6 expressing human keratinocytes in response to therapeutic agents.

Authors:  Zhi-Guo Liu; Li-Na Zhao; Ying-Wang Liu; Ting-Ting Li; Dai-Ming Fan; Jason J Chen
Journal:  J Mol Biol       Date:  2007-09-18       Impact factor: 5.469

3.  Conformational bias imposed by source microseeds results in structural ambiguity.

Authors:  Netanel Tzarum; David Engelberg; Oded Livnah
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2011-07-13

4.  PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents.

Authors:  Gautam Adhikary; Yap Ching Chew; E Albert Reece; Richard L Eckert
Journal:  J Invest Dermatol       Date:  2010-05-06       Impact factor: 8.551

5.  Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2.

Authors:  Jose Sangerman; Moo Seung Lee; Xiao Yao; Eugene Oteng; Cheng-Hui Hsiao; Wei Li; Sima Zein; Solomon F Ofori-Acquah; Betty S Pace
Journal:  Blood       Date:  2006-08-08       Impact factor: 22.113

6.  Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression.

Authors:  Kamalika Saha; Richard L Eckert
Journal:  J Biol Chem       Date:  2015-04-07       Impact factor: 5.157

Review 7.  p38 Mitogen-activated protein kinase regulates myelination.

Authors:  Jeffery D Haines; Gabriela Fragoso; Shireen Hossain; Walter E Mushynski; Guillermina Almazan
Journal:  J Mol Neurosci       Date:  2007-11-10       Impact factor: 3.444

8.  Development of a novel bioinformatics tool for in silico validation of protein interactions.

Authors:  Nicola Barbarini; Luca Simonelli; Alberto Azzalin; Sergio Comincini; Riccardo Bellazzi
Journal:  J Biomed Biotechnol       Date:  2010-06-07

9.  Role of p38 mitogen-activated protein kinase in middle ear mucosa hyperplasia during bacterial otitis media.

Authors:  Sean D Palacios; Kwang Pak; Alexander Z Rivkin; Ayse G Kayali; Darrell Austen; Christoph Aletsee; Asa Melhus; Nicholas J G Webster; Allen F Ryan
Journal:  Infect Immun       Date:  2004-08       Impact factor: 3.441

10.  Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex.

Authors:  Tatiana Efimova; Ann-Marie Broome; Richard L Eckert
Journal:  Mol Cell Biol       Date:  2004-09       Impact factor: 4.272
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