Literature DB >> 12713331

Diastereoselective synthesis of piperazines by manganese-mediated reductive cyclization.

Gregory J Mercer1, Matthew S Sigman.   

Abstract

A simple and effective synthesis of trans aryl-substituted piperazines using a Brønsted acid and manganese(0) is described. [reaction: see text]

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Year:  2003        PMID： 12713331     DOI： 10.1021/ol034469l

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Palladium-catalyzed alkene carboamination reactions for the synthesis of substituted piperazines.

Authors:  Josephine S Nakhla; Danielle M Schultz; John P Wolfe
Journal:  Tetrahedron       Date:  2009-09-15       Impact factor: 2.457

Review 2.  Proton-Coupled Electron Transfer in Organic Synthesis: Fundamentals, Applications, and Opportunities.

Authors:  David C Miller; Kyle T Tarantino; Robert R Knowles
Journal:  Top Curr Chem (Cham)       Date:  2016-05-09

3.  A concise asymmetric synthesis of cis-2,6-disubstituted N-aryl piperazines via Pd-catalyzed carboamination reactions.

Authors:  Josephine S Nakhla; John P Wolfe
Journal:  Org Lett       Date:  2007-07-25       Impact factor: 6.005

4.  Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics.

Authors:  Samuel Suárez-Pantiga; Kilian Colas; Magnus J Johansson; Abraham Mendoza
Journal:  Angew Chem Int Ed Engl       Date:  2015-09-04       Impact factor: 15.336
  4 in total

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