Literature DB >> 12713330

Carboxylate-directed highly stereoselective homogeneous hydrogenation of cyclic olefins with Wilkinson's catalyst.

Mingbao Zhang1, Lei Zhu, Xin Ma, Miao Dai, Derek Lowe.   

Abstract

A highly efficient diastereoselective, carboxylate-directed homogeneous hydrogenation of cyclic olefins with use of Wilkinson's catalyst is described. Under the optimized reaction conditions, better than 99% de was achieved. The experimental protocol is very simple and readily amenable to scale-up. [reaction: see text]

Entities:  

Year:  2003        PMID: 12713330     DOI: 10.1021/ol034464o

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Discovery of potent and specific dihydroisoxazole inhibitors of human transglutaminase 2.

Authors:  Cornelius Klöck; Zachary Herrera; Megan Albertelli; Chaitan Khosla
Journal:  J Med Chem       Date:  2014-10-31       Impact factor: 7.446

2.  Synthesis of the Mixed Acetal Segment of S-Glyceroplasmalopsychosine.

Authors:  Ajit K Parhi; David R Mootoo; Richard W Franck
Journal:  Tetrahedron       Date:  2008-10-13       Impact factor: 2.457

  2 in total

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