OBJECTIVE: The purpose of this study was to identify the medications that are consumed by a rural obstetric population during pregnancy. STUDY DESIGN: Over a period of 26 months, pregnant women were interviewed about medication use. Interviews on subsequent visits provided a longitudinal study of medication usage and discontinuation. Trend differences were analyzed according to the number of medications, the trimester of use, and insurance status. RESULTS: Five hundred seventy-eight participants had 2086 interviews. The compilation of the interviews showed that 95.8% of the participants took prescription medications, 92.6% of the participants self-medicated with over-the-counter medications, and 45.2% of the participants used herbal medications. Over time, consumption of over-the-counter medications exceeded prescription medication use. Fifteen percent of the pregnant women took ibuprofen at some point during the pregnancy (5.7% in the third trimester). Eight percent of the women were noncompliant and 20% incompletely compliant with prenatal vitamin and mineral formulations. CONCLUSION: Medication use was substantial in this population. Medications (eg, ibuprofen) that are contraindicated in pregnancy were used at unexpectedly high rates. Of the three medication classes, over-the-counter medications were used most frequently.
OBJECTIVE: The purpose of this study was to identify the medications that are consumed by a rural obstetric population during pregnancy. STUDY DESIGN: Over a period of 26 months, pregnant women were interviewed about medication use. Interviews on subsequent visits provided a longitudinal study of medication usage and discontinuation. Trend differences were analyzed according to the number of medications, the trimester of use, and insurance status. RESULTS: Five hundred seventy-eight participants had 2086 interviews. The compilation of the interviews showed that 95.8% of the participants took prescription medications, 92.6% of the participants self-medicated with over-the-counter medications, and 45.2% of the participants used herbal medications. Over time, consumption of over-the-counter medications exceeded prescription medication use. Fifteen percent of the pregnant women took ibuprofen at some point during the pregnancy (5.7% in the third trimester). Eight percent of the women were noncompliant and 20% incompletely compliant with prenatal vitamin and mineral formulations. CONCLUSION: Medication use was substantial in this population. Medications (eg, ibuprofen) that are contraindicated in pregnancy were used at unexpectedly high rates. Of the three medication classes, over-the-counter medications were used most frequently.
Authors: Jerrie S Refuerzo; Biana Godin; Karen Bishop; Srimeenakshi Srinivasan; Shinil K Shah; Sarah Amra; Susan M Ramin; Mauro Ferrari Journal: Am J Obstet Gynecol Date: 2011-04-08 Impact factor: 8.661
Authors: Kristen A Johnson; Lindsey A Sjaarda; Sunni L Mumford; Rebecca A Garbose; Karen C Schliep; Donald Mattison; Neil J Perkins; Jean Wactawski-Wende; Enrique F Schisterman Journal: Pharmacoepidemiol Drug Saf Date: 2016-03-08 Impact factor: 2.890
Authors: Ariel R Topletz; Huong N Le; Nora Lee; John D Chapman; Edward J Kelly; Joanne Wang; Nina Isoherranen Journal: Drug Metab Dispos Date: 2012-11-13 Impact factor: 3.922