Literature DB >> 12712107

Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population.

Douglas D Glover1, Mayur Amonkar, Blanche F Rybeck, Timothy S Tracy.   

Abstract

OBJECTIVE: The purpose of this study was to identify the medications that are consumed by a rural obstetric population during pregnancy. STUDY
DESIGN: Over a period of 26 months, pregnant women were interviewed about medication use. Interviews on subsequent visits provided a longitudinal study of medication usage and discontinuation. Trend differences were analyzed according to the number of medications, the trimester of use, and insurance status.
RESULTS: Five hundred seventy-eight participants had 2086 interviews. The compilation of the interviews showed that 95.8% of the participants took prescription medications, 92.6% of the participants self-medicated with over-the-counter medications, and 45.2% of the participants used herbal medications. Over time, consumption of over-the-counter medications exceeded prescription medication use. Fifteen percent of the pregnant women took ibuprofen at some point during the pregnancy (5.7% in the third trimester). Eight percent of the women were noncompliant and 20% incompletely compliant with prenatal vitamin and mineral formulations.
CONCLUSION: Medication use was substantial in this population. Medications (eg, ibuprofen) that are contraindicated in pregnancy were used at unexpectedly high rates. Of the three medication classes, over-the-counter medications were used most frequently.

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Year:  2003        PMID: 12712107     DOI: 10.1067/mob.2003.223

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  60 in total

1.  Case-control analysis of maternal prenatal analgesic use and cardiovascular malformations: Baltimore-Washington Infant Study.

Authors:  Courtney A Marsh; Janet D Cragan; C J Alverson; Adolfo Correa
Journal:  Am J Obstet Gynecol       Date:  2014-03-27       Impact factor: 8.661

2.  Value of Genetics-informed Drug Dosing Guidance in Pregnant Women: A Needs Assessment with Obstetric Healthcare Providers at Johns Hopkins.

Authors:  Casey L Overby; Phillip Thompkins; Harold Lehmann; Christopher G Chute; Jeanne S Sheffield
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

3.  Determinants of self medication practices among pregnant women in Ibadan, Nigeria.

Authors:  Kazeem B Yusuff; Louis-Domeih Omarusehe
Journal:  Int J Clin Pharm       Date:  2011-09-01

4.  Predictors of the use of medications before and during pregnancy.

Authors:  Marina Odalovic; Sandra Vezmar Kovacevic; Hedvig Nordeng; Katarina Ilic; Ana Sabo; Ljiljana Tasic
Journal:  Int J Clin Pharm       Date:  2013-02-07

5.  Size of the nanovectors determines the transplacental passage in pregnancy: study in rats.

Authors:  Jerrie S Refuerzo; Biana Godin; Karen Bishop; Srimeenakshi Srinivasan; Shinil K Shah; Sarah Amra; Susan M Ramin; Mauro Ferrari
Journal:  Am J Obstet Gynecol       Date:  2011-04-08       Impact factor: 8.661

Review 6.  Altered drug metabolism during pregnancy: hormonal regulation of drug-metabolizing enzymes.

Authors:  Hyunyoung Jeong
Journal:  Expert Opin Drug Metab Toxicol       Date:  2010-06       Impact factor: 4.481

Review 7.  Pharmacogenetics and individualizing drug treatment during pregnancy.

Authors:  David M Haas
Journal:  Pharmacogenomics       Date:  2014-01       Impact factor: 2.533

8.  Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes?

Authors:  Nina Isoherranen; Kenneth E Thummel
Journal:  Drug Metab Dispos       Date:  2013-02       Impact factor: 3.922

9.  Patterns and prevalence of medication use across the menstrual cycle among healthy, reproductive aged women.

Authors:  Kristen A Johnson; Lindsey A Sjaarda; Sunni L Mumford; Rebecca A Garbose; Karen C Schliep; Donald Mattison; Neil J Perkins; Jean Wactawski-Wende; Enrique F Schisterman
Journal:  Pharmacoepidemiol Drug Saf       Date:  2016-03-08       Impact factor: 2.890

10.  Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy.

Authors:  Ariel R Topletz; Huong N Le; Nora Lee; John D Chapman; Edward J Kelly; Joanne Wang; Nina Isoherranen
Journal:  Drug Metab Dispos       Date:  2012-11-13       Impact factor: 3.922

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