Literature DB >> 12711616

The ups and downs of Gs- to Gi-protein switching.

Stephen J Hill1, Jillian G Baker.   

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Year:  2003        PMID: 12711616      PMCID: PMC1573788          DOI: 10.1038/sj.bjp.0705192

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


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  11 in total

1.  Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).

Authors:  J D Kilts; M A Gerhardt; M D Richardson; G Sreeram; G B Mackensen; H P Grocott; W D White; R D Davis; M F Newman; J G Reves; D A Schwinn; M M Kwatra
Journal:  Circ Res       Date:  2000-10-13       Impact factor: 17.367

2.  Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.

Authors:  Robert J Lefkowitz; Kristen L Pierce; Louis M Luttrell
Journal:  Mol Pharmacol       Date:  2002-11       Impact factor: 4.436

3.  Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins.

Authors:  K Wenzel-Seifert; R Seifert
Journal:  Mol Pharmacol       Date:  2000-11       Impact factor: 4.436

4.  beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf.

Authors:  J M Schmitt; P J Stork
Journal:  J Biol Chem       Date:  2000-08-18       Impact factor: 5.157

5.  Cardiac-specific overexpression of human beta2 adrenoceptors in mice exposes coupling to both Gs and Gi proteins.

Authors:  A R G Hasseldine; E A Harper; J W Black
Journal:  Br J Pharmacol       Date:  2003-04       Impact factor: 8.739

6.  Caveolar localization dictates physiologic signaling of beta 2-adrenoceptors in neonatal cardiac myocytes.

Authors:  Yang Xiang; Vitalyi O Rybin; Susan F Steinberg; Brian Kobilka
Journal:  J Biol Chem       Date:  2002-07-03       Impact factor: 5.157

7.  Beta(2)-adrenergic receptor lacking the cyclic AMP-dependent protein kinase consensus sites fully activates extracellular signal-regulated kinase 1/2 in human embryonic kidney 293 cells: lack of evidence for G(s)/G(i) switching.

Authors:  Jacqueline Friedman; Bonita Babu; Richard B Clark
Journal:  Mol Pharmacol       Date:  2002-11       Impact factor: 4.436

8.  Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor.

Authors:  R A Bond; P Leff; T D Johnson; C A Milano; H A Rockman; T R McMinn; S Apparsundaram; M F Hyek; T P Kenakin; L F Allen
Journal:  Nature       Date:  1995-03-16       Impact factor: 49.962

9.  Age increases cardiac Galpha(i2) expression, resulting in enhanced coupling to G protein-coupled receptors.

Authors:  Jason D Kilts; Toshimasa Akazawa; Mark D Richardson; Madan M Kwatra
Journal:  J Biol Chem       Date:  2002-06-13       Impact factor: 5.157

10.  Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes.

Authors:  R P Xiao; P Avdonin; Y Y Zhou; H Cheng; S A Akhter; T Eschenhagen; R J Lefkowitz; W J Koch; E G Lakatta
Journal:  Circ Res       Date:  1999 Jan 8-22       Impact factor: 17.367

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  10 in total

1.  Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR).

Authors:  Pavel Gris; Philip Cheng; John Pierson; William Maixner; Luda Diatchenko
Journal:  Methods Mol Biol       Date:  2010

2.  Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain.

Authors:  Sachia G Khasar; Jennifer Burkham; Olayinka A Dina; Adrienne S Brown; Oliver Bogen; Nicole Alessandri-Haber; Paul G Green; David B Reichling; Jon D Levine
Journal:  J Neurosci       Date:  2008-05-28       Impact factor: 6.167

3.  On the G protein-coupling selectivity of the native A2B adenosine receptor.

Authors:  Zhan-Guo Gao; Asuka Inoue; Kenneth A Jacobson
Journal:  Biochem Pharmacol       Date:  2017-12-07       Impact factor: 5.858

Review 4.  A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases.

Authors:  W J Poppinga; P Muñoz-Llancao; C González-Billault; M Schmidt
Journal:  Br J Pharmacol       Date:  2014-12       Impact factor: 8.739

5.  Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression.

Authors:  Mark J Wall; Emily Hill; Robert Huckstepp; Kerry Barkan; Giuseppe Deganutti; Michele Leuenberger; Barbara Preti; Ian Winfield; Sabrina Carvalho; Anna Suchankova; Haifeng Wei; Dewi Safitri; Xianglin Huang; Wendy Imlach; Circe La Mache; Eve Dean; Cherise Hume; Stephanie Hayward; Jess Oliver; Fei-Yue Zhao; David Spanswick; Christopher A Reynolds; Martin Lochner; Graham Ladds; Bruno G Frenguelli
Journal:  Nat Commun       Date:  2022-07-18       Impact factor: 17.694

6.  Activation of Gi induces mechanical hyperalgesia poststress or inflammation.

Authors:  O A Dina; S G Khasar; R W Gear; J D Levine
Journal:  Neuroscience       Date:  2009-03-09       Impact factor: 3.590

7.  Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells.

Authors:  Ramanaiah Mamillapalli; Joshua VanHouten; Walter Zawalich; John Wysolmerski
Journal:  J Biol Chem       Date:  2008-07-11       Impact factor: 5.157

Review 8.  Stratified approaches to the treatment of asthma.

Authors:  Stephen T Holgate
Journal:  Br J Clin Pharmacol       Date:  2013-08       Impact factor: 4.335

9.  A New Generation of FRET Sensors for Robust Measurement of Gαi1, Gαi2 and Gαi3 Activation Kinetics in Single Cells.

Authors:  Jakobus van Unen; Anette D Stumpf; Benedikt Schmid; Nathalie R Reinhard; Peter L Hordijk; Carsten Hoffmann; Theodorus W J Gadella; Joachim Goedhart
Journal:  PLoS One       Date:  2016-01-22       Impact factor: 3.240

10.  Clenbuterol Induces Cell Cycle Arrest in C2C12 Myoblasts by Delaying p27 Degradation through β-arrestin 2 Signaling.

Authors:  Min Chen; Chuncheng Liu; Meng Wang; Hong Wang; Kuo Zhang; Yu Zheng; Zhengquan Yu; Xiangdong Li; Wei Guo; Ning Li; Qingyong Meng
Journal:  Int J Biol Sci       Date:  2017-10-17       Impact factor: 6.580

  10 in total

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