Literature DB >> 12711360

The role of the CD44/ezrin complex in cancer metastasis.

Tracey A Martin1, Gregory Harrison, Robert E Mansel, Wen G Jiang.   

Abstract

CD44 is a cell adhesion molecule that was traditionally known as 'homing receptor'. This molecule is known to interact with the ezrin family (ERM family) members and form a complex that plays diverse roles within both normal and abnormal cells, particularly cancer cells. CD44 and ezrin and their respective complex have properties suggesting that they may be important in the process of tumour-endothelium interactions, cell migrations, cell adhesion, tumour progression and metastasis. This article reviews the role of CD44, ezrin family and the CD44/ezrin complex in cancer cells and their clinical impact in patients with cancer.

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Year:  2003        PMID： 12711360     DOI： 10.1016/s1040-8428(02)00172-5

Source DB:  PubMed          Journal:  Crit Rev Oncol Hematol        ISSN： 1040-8428            Impact factor:   6.312


  77 in total

1.  A positive feedback loop couples Ras activation and CD44 alternative splicing.

Authors:  Chonghui Cheng; Michael B Yaffe; Phillip A Sharp
Journal:  Genes Dev       Date:  2006-07-01       Impact factor: 11.361

2.  Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of adhesion molecule CD44.

Authors:  Tomoyuki Mori; Ken Kitano; Shin-ichi Terawaki; Ryoko Maesaki; Toshio Hakoshima
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-09-19

3.  Atypical protein kinase C (iota) activates ezrin in the apical domain of intestinal epithelial cells.

Authors:  Flavia A Wald; Andrea S Oriolo; Anastasia Mashukova; Nevis L Fregien; Amber H Langshaw; Pedro J I Salas
Journal:  J Cell Sci       Date:  2008-02-12       Impact factor: 5.285

4.  CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high-fat-fed C57BL/6 mice.

Authors:  Annie Hasib; Chandani K Hennayake; Deanna P Bracy; Aimée R Bugler-Lamb; Louise Lantier; Faisel Khan; Michael L J Ashford; Rory J McCrimmon; David H Wasserman; Li Kang
Journal:  Am J Physiol Endocrinol Metab       Date:  2019-09-24       Impact factor: 4.310

5.  CD44v6 dependence of premetastatic niche preparation by exosomes.

Authors:  Thorsten Jung; Donatello Castellana; Pamela Klingbeil; Ines Cuesta Hernández; Mario Vitacolonna; David J Orlicky; Steve R Roffler; Pnina Brodt; Margot Zöller
Journal:  Neoplasia       Date:  2009-10       Impact factor: 5.715

6.  Increase in ezrin expression from benign to malignant breast tumours.

Authors:  Daphne Gschwantler-Kaulich; Camilla Natter; Stefan Steurer; Ingrid Walter; Almut Thomas; Mohamed Salama; Christian F Singer
Journal:  Cell Oncol (Dordr)       Date:  2013-10-16       Impact factor: 6.730

7.  N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer.

Authors:  Tracey A Martin; Gordon Pereira; Gareth Watkins; Robert E Mansel; Wen G Jiang
Journal:  Clin Exp Metastasis       Date:  2007-11-06       Impact factor: 5.150

Review 8.  CD44 in cancer progression: adhesion, migration and growth regulation.

Authors:  R Marhaba; M Zöller
Journal:  J Mol Histol       Date:  2004-03       Impact factor: 2.611

Review 9.  Osteosarcoma development and stem cell differentiation.

Authors:  Ni Tang; Wen-Xin Song; Jinyong Luo; Rex C Haydon; Tong-Chuan He
Journal:  Clin Orthop Relat Res       Date:  2008-06-18       Impact factor: 4.176

10.  Metastatic and prognostic factors in patients with alveolar echinococcosis.

Authors:  Hui Wang; Chang Lu; Xia Liu; Wei Zhang
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01
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