Literature DB >> 12710573

Palliation and survival in metastatic tumors compressing the cauda equina: a 19-year radiotherapeutic experience.

Federico L Ampil1, Gloria Caldito, Maureen Heldmann.   

Abstract

UNLABELLED: PURPOSE; Radiotherapy (RT) offers a means of promoting an acceptable quality of life in people with incurable cancer. We reviewed our radiotherapeutic experience of metastatic tumors compressing the cauda equina (MTCCE) because large case series and achieved palliation in these patients are infrequently documented in the literature.
METHODS: Seventy-six individuals undergoing RT for MTCCE were identified from a 19-year period (1981-1999). Treatment responses and survival were assessed.
RESULTS: Pain relief was complete in 94%, partial in 3%, and not achieved in 3% of the 32 evaluated patients. Complete resolution of impaired sensation in the lower limbs occurred in three cases, and of anal or bladder sphincter dysfunction in three persons also. Among the 28 evaluable individuals with lower extremity motion impairment, 11 (39%) were nonambulatory and 17 (61%) were ambulatory following treatment. The overall median survival was 3 months; the survival rate at 1 year was 18% and at 3 years 8%.
CONCLUSION: Although long-term survival is not to be expected, the usefulness of RT for palliation of MTCCE may be trusted.

Entities:  

Mesh:

Year:  2003        PMID: 12710573     DOI: 10.1089/10966210360510091

Source DB:  PubMed          Journal:  J Palliat Med        ISSN: 1557-7740            Impact factor:   2.947


  3 in total

1.  Cauda equina syndrome caused by lumbar leptomeningeal metastases from lung adenocarcinoma mimicking a schwannoma.

Authors:  Giovanni Federico Nicoletti; Giuseppe Emmanuele Umana; Francesca Graziano; Alessandro Calì; Marco Fricia; Salvatore Cicero; Gianluca Scalia
Journal:  Surg Neurol Int       Date:  2020-08-01

2.  A case of indirect cauda equina syndrome from metastatic prostate cancer.

Authors:  Shilo Lefresne; Alysa Fairchild; Aalo Bistritz; Peter Venner; Don Yee
Journal:  Can Urol Assoc J       Date:  2009-08       Impact factor: 1.862

3.  Cauda equine syndrome as the primary symptom of leptomeningeal metastases from lung cancer: a case report and review of literature.

Authors:  Yang Liu; Bin Wang; Yongxiang Qian; Dongmei Di; Min Wang; Xiaoying Zhang
Journal:  Onco Targets Ther       Date:  2018-08-20       Impact factor: 4.147

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.