| Literature DB >> 12709842 |
D J Hoban1, S K Bouchillon, J L Johnson, G G Zhanel, D L Butler, K A Saunders, L A Miller, J A Poupard.
Abstract
The present study was conducted to determine the in vitro activity of amoxicillin-clavulanic acid compared to that of four newer antimicrobial agents (ampicillin, azithromycin, cefuroxime and trimethoprim-sulfamethoxazole). All of the agents were tested against 21232 recent clinical isolates encompassing 37 species submitted from 16 European countries between 1997 and 1999. After 20 years of clinical use, amoxicillin-clavulanic acid continues to retain much of its initial activity against targeted gram-positive organisms, selected gram-negative organisms and major respiratory pathogens.Entities:
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Year: 2003 PMID： 12709842 DOI： 10.1007/s10096-002-0876-0
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN： 0934-9723 Impact factor: 3.267