Literature DB >> 12709815

Confirmation of PSORS psoriasis susceptibility loci in a Chinese population.

Jie Zheng1, Shiyi Jin, Ruofei Shi.   

Abstract

We investigated 38 Chinese psoriasis families with 19 reported microsatellite markers. Families comprised a total of 96 affected and 92 unaffected individuals. Genotyping results were analyzed using parametric and nonparametric linkage analysis. Our results confirmed the published linkage with the PSORS1 locus, as well as the PSORS2 locus, which has not been previously shown in the Chinese population. Significant two-point LOD scores were obtained in a parametric linkage analysis with markers D6S1610 and D17S944. Nonparametric linkage values greater than 1.6 ( P<0.05) were obtained with markers D6S1610, D17S944 and D17S785.

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Year:  2003        PMID： 12709815     DOI： 10.1007/s00403-003-0383-x

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  2 in total

1.  Analysis of RUNX1 binding site and RAPTOR polymorphisms in psoriasis: no evidence for association despite adequate power and evidence for linkage.

Authors:  P Stuart; R P Nair; G R Abecasis; I Nistor; R Hiremagalore; N V Chia; Z S Qin; R A Thompson; S Jenisch; M Weichenthal; J Janiga; H W Lim; E Christophers; J J Voorhees; J T Elder
Journal:  J Med Genet       Date:  2005-05-27       Impact factor: 6.318

2.  Association analysis identifies ZNF750 regulatory variants in psoriasis.

Authors:  Ramon Y Birnbaum; Genki Hayashi; Idan Cohen; Annie Poon; Haoyan Chen; Ernest T Lam; Pui-Yan Kwok; Ohad S Birk; Wilson Liao
Journal:  BMC Med Genet       Date:  2011-12-20       Impact factor: 2.103
  2 in total

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