Literature DB >> 12709128

Mechanical properties of the skin: a comparison between two suction cup methods.

L Pedersen1, B Hansen, G B E Jemec.   

Abstract

BACKGROUND/AIMS: The objective measure of mechanical properties of the skin is relevant to the clinician as well as to the researcher concerned with skin physiology. The lack of standardization among methods used to obtain visco-elastic data from the skin is however, apparent and represents an obstacle to comparison of the results derived from the various studies concerning the subject.
METHODS: The mechanical properties of the ventral forearm were studied in 35 healthy volunteers. The Dermaflex and the DermaLab (Both Cortex Technology, Hadsund, Denmark) were compared. The results were analyzed with descriptive statistics and correlations using non-parametric methods. Measurement accuracy was assessed using coefficient of variation. Sub analysis was made in groups according to gender and age.
RESULTS: The overall correlations between the two methods were moderate (r = 0.383-0.437). A greater coefficient of variation was found in the DermaLab machine. Significant differences were found between all values of both methods when comparing the mechanical properties of the skin in 30-39 years olds versus the group of 40-58 years olds. No differences were found between the genders.
CONCLUSIONS: The results indicate that both methods are useful in the study of the mechanical aspects of the skin, especially for detecting age-related changes. The Dermaflex seems to produce more accurate for data. This is thought to be due to the conceptual design differences between the two methods. The methods measure related but not identical values of the mechanical properties of the skin, as reflected by the limited positive correlation between them.

Mesh:

Year:  2003        PMID: 12709128     DOI: 10.1034/j.1600-0846.2003.00021.x

Source DB:  PubMed          Journal:  Skin Res Technol        ISSN: 0909-752X            Impact factor:   2.365


  5 in total

1.  Development of compression-controlled low-level laser probe system: towards clinical application.

Authors:  Changmin Yeo; Taeyoon Son; Junghwan Park; Young-Heum Lee; Kiwoon Kwon; J Stuart Nelson; Byungjo Jung
Journal:  Lasers Med Sci       Date:  2010-09       Impact factor: 3.161

2.  Characterization of skin abnormalities in a mouse model of osteogenesis imperfecta using high resolution magnetic resonance imaging and Fourier transform infrared imaging spectroscopy.

Authors:  H C Canuto; K W Fishbein; A Huang; S B Doty; R A Herbert; J Peckham; N Pleshko; R G Spencer
Journal:  NMR Biomed       Date:  2011-08-15       Impact factor: 4.044

3.  Alternative splicing and tissue-specific elastin misassembly act as biological modifiers of human elastin gene frameshift mutations associated with dominant cutis laxa.

Authors:  Hideki Sugitani; Eiichi Hirano; Russell H Knutsen; Adrian Shifren; Jessica E Wagenseil; Christopher Ciliberto; Beth A Kozel; Zsolt Urban; Elaine C Davis; Thomas J Broekelmann; Robert P Mecham
Journal:  J Biol Chem       Date:  2012-05-09       Impact factor: 5.157

4.  Biomechanical properties of the skin in cutis laxa.

Authors:  Beth A Kozel; Chi-Ting Su; Joshua R Danback; Ryan L Minster; Suneeta Madan-Khetarpal; Juliann S McConnell; Meghan K Mac Neal; Kara L Levine; Robert C Wilson; Frank C Sciurba; Zsolt Urban
Journal:  J Invest Dermatol       Date:  2014-05-20       Impact factor: 8.551

5.  Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers.

Authors:  Michael E O'Brien; Divay Chandra; Robert C Wilson; Chad M Karoleski; Carl R Fuhrman; Joseph K Leader; Jiantao Pu; Yingze Zhang; Alison Morris; Seyed Nouraie; Jessica Bon; Zsolt Urban; Frank C Sciurba
Journal:  Respir Res       Date:  2019-06-24
  5 in total

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