Literature DB >> 12707645

Topical nasal anesthesia for transnasal fiberoptic laryngoscopy: a prospective, double-blind, cross-over study.

Paul E Johnson1, Peter C Belafsky, Gregory N Postma.   

Abstract

BACKGROUND: Transnasal fiberoptic laryngoscopy (TFL) is frequently performed by otolaryngologists, speech language pathologists, and various other health care providers. Historically, topical sprays have been administered to patients to decongest and anesthetize the nasal mucosa, thus minimizing the discomfort of the procedure. Recently, it was reported that patients undergoing TFL with topical anesthesia experienced no improvement in comfort compared with those who received oxymetazoline or saline. This observation is in direct opposition to our clinical experience that patients tolerate the procedure better with topical anesthesia.
PURPOSE: We sought to compare patient comfort levels during TFL after the administration of cocaine, oxymetazoline, or saline.
METHODS: Fifteen subjects undergoing TFL were prospectively evaluated. Each had TFL performed on 3 separate occasions. Before TFL, each patient received either 4% cocaine, 0.05% oxymetazoline, or saline topically administered via an atomizer to both nasal cavities (1 spray of 2-second duration). By the conclusion of the study, each patient had undergone TFL with each of the test agents. The subjects rated the discomfort they experienced on a scale ranging from 1 (minimal discomfort) to 5 (severe discomfort). Both patient and examiner were blinded to the test agent used.
RESULTS: The mean nasal discomfort score for saline was 2.8 +/- 1.1. The scores for oxymetazoline and cocaine were 3.4 +/- 0.9 and 2.0 +/- 0.9, respectively. Compared with saline and oxymetazoline independently, TFL with topical cocaine appeared to provide more comfort (P < 0.05 and P < 0.005).
CONCLUSION: The continued routine use of topical anesthetics such as cocaine before the performance of TFL is justified because it significantly decreases the patient's discomfort.

Entities:  

Mesh:

Year:  2003        PMID: 12707645     DOI: 10.1016/S0194-59980223294-5

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   5.591


  7 in total

Review 1.  Topical anesthetic preparations for rigid and flexible endoscopy: a meta-analysis.

Authors:  Se Hwan Hwang; Chan-Soon Park; Byung Guk Kim; Jin Hee Cho; Jun Myung Kang
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-03-29       Impact factor: 2.503

Review 2.  History of Fiberoptic Endoscopic Evaluation of Swallowing for Evaluation and Management of Pharyngeal Dysphagia: Changes over the Years.

Authors:  Susan E Langmore
Journal:  Dysphagia       Date:  2017-01-18       Impact factor: 3.438

3.  A randomized trial of topical anesthesia comparing lidocaine versus lidocaine plus xylometazoline for unsedated transnasal upper gastrointestinal endoscopy.

Authors:  Justin Cheung; Karen Goodman; Robert Bailey; Richard Fedorak; John Morse; Mario Millan; Tom Guzowski; Sander Veldhuyzen van Zanten
Journal:  Can J Gastroenterol       Date:  2010-05       Impact factor: 3.522

4.  Effects of topical nasal anesthetic on fiberoptic endoscopic examination of swallowing with sensory testing (FEESST).

Authors:  Erin E Kamarunas; Gary H McCullough; Tiffany J Guidry; Mark Mennemeier; Keith Schluterman
Journal:  Dysphagia       Date:  2013-07-05       Impact factor: 3.438

5.  Adjustments of non-invasive ventilation and mechanically assisted cough by combining ultrasound imaging of the larynx with transnasal fibre-optic laryngoscopy: a protocol for an experimental study.

Authors:  Anne Kristine Brekka; Maria Vollsæter; George Ntoumenopoulos; Hege Havstad Clemm; Thomas Halvorsen; Ola Drange Røksund; Tiina Maarit Andersen
Journal:  BMJ Open       Date:  2022-05-25       Impact factor: 3.006

6.  Bacterial contamination of multiple-use atomizers commonly used in Japan.

Authors:  Katsuhisa Ikeda; Yoko Sakai; Takuo Haruyama; Narumi Misawa; Naritake Misawa; Satoshi Hori; Takeshi Kusunoki; Masayuki Furukawa; Hidenori Yokoi; Naoko Yokoi; Yukiko Ichihari; Kenji Kawano; Fumihiko Matsumoto; Chieri Hayashi; T Yao; Yuya Narui; Takashi Iizuka; Shin Ito; Ayako Inoshita; Misato Kasai; Tatsuya Saito; Akira Minekawa; Shin-Ichi Oba; Yoko Cho
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2009-09-27

7.  Premedication Methods in Nasal Endoscopy: A Prospective, Randomized, Double-Blind Study.

Authors:  Mehmet İlhan Şahin; Kerem Kökoğlu; Şafak Güleç; İbrahim Ketenci; Yaşar Ünlü
Journal:  Clin Exp Otorhinolaryngol       Date:  2016-07-27       Impact factor: 3.372

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.