| Literature DB >> 12707440 |
Fernando L Pagan1, John A Butman, James M Dambrosia, Mark Hallett.
Abstract
The pathologic substrate of essential tremor (ET) remains unknown. The authors studied 10 patients with ET and 10 volunteers using a multislice MR spectroscopy imaging sequence. Left and right cerebellar hemisphere NAA/CR and NAA/Cho ratios were significantly smaller in the ET patients than healthy subjects. The authors' data suggest that the decreased NAA/Cr and NAA/Cho ratios within the cerebellum may represent an abnormality in neuronal function.Entities:
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Year: 2003 PMID： 12707440 DOI： 10.1212/01.wnl.0000065885.15875.0d
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910