| Literature DB >> 12706442 |
Georg Lautscham1, Alan Rickinson, Neil Blake.
Abstract
For recognition by CD8(+) lymphocytes, peptides derived from cytosolically processed antigen need to access MHC class I molecules en route to the target cell surface. This normally requires peptide transport into the endoplasmic reticulum via the transporter associated with antigen presentation (TAP) complex. However, as recent work with Epstein-Barr virus illustrates, TAP-independent presentation pathways also exist and are growing in number.Entities:
Mesh:
Substances:
Year: 2003 PMID: 12706442 DOI: 10.1016/s1286-4579(03)00031-5
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700