Literature DB >> 12706005

Fournier's gangrene: an analysis of repeated surgical debridement.

Sam N Chawla1, Christina Gallop, Jack H Mydlo.   

Abstract

OBJECTIVES: We wanted to determine if there was a difference in outcome for those patients with Fournier's disease who underwent numerous debridements as opposed to only one initial debridement.
METHODS: The records of 19 patients with the diagnosis of Fournier's gangrene were reviewed retrospectively at our institution. Special attention was placed on demographic data, primary managing service, as well as wound cultures, and the number and timing of surgical debridements. Patients were also classified by a collection of variables at presentation and given a score named the Fournier's Severity Index. We utilised the Fournier's Severity Index (FSI) as developed by Laor et al. which included a number of vital sign data as well as laboratory values collected at admission in the emergency room.
RESULTS: The average FSI was 9.1 ranging from 0 to 15. The mean FSI of survivors was 8.6 versus 12.4 of non-survivors. The surgical management of this disease process was also critically examined. The average number of repeated debridements was 3.5 ranging from 1 to 8. Both the FSI and the number of debridements were attempted to be used to predict outcome. Outcome was measured in the variables length of stay (days) and survival. A regression analysis revealed the number of debridements to be positively related to the length of stay (LOS). This was the opposite as expected at the beginning of the study. Also FSI was not predictive of LOS.
CONCLUSIONS: Fournier's gangrene is a disease process with a wide variability in presentation. The FSI does give some indication about the likelihood of survival based on variables which can be recorded upon presentation. It also provides an efficient way to characterize the acuity of presentation and compare patients. While the repeated nature of debridements may be considered the accepted standard of care in these patients, this was not found to be predictive of outcome.

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Year:  2003        PMID: 12706005     DOI: 10.1016/s0302-2838(03)00102-7

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


  31 in total

1.  Fournier's gangrene: analysis of prognostic variables in 34 patients.

Authors:  A García Marín; J Martín Gil; A Vaquero Rodríguez; T Sánchez Rodríguez; J de Tomás Palacios; J Lago Oliver; F Turégano Fuentes
Journal:  Eur J Trauma Emerg Surg       Date:  2010-05-27       Impact factor: 3.693

Review 2.  Fournier's gangrene and its emergency management.

Authors:  A Thwaini; A Khan; A Malik; J Cherian; J Barua; I Shergill; K Mammen
Journal:  Postgrad Med J       Date:  2006-08       Impact factor: 2.401

3.  Vacuum-assisted closure in the treatment of perineal necrotizing skin and soft tissue infections.

Authors:  Régis Bronchard; Cyrille de Vaumas; Sigismond Lasocki; Khalil Jabbour; Arnaud Geffroy; Nathalie Kermarrec; Philippe Montravers
Journal:  Intensive Care Med       Date:  2008-04-04       Impact factor: 17.440

4.  Fournier gangrene as a manifestation of undiagnosed metastatic perforated colorectal cancer.

Authors:  Cyrus C Chan; Mallory Williams
Journal:  Int Surg       Date:  2013 Jan-Mar

Review 5.  Rectal cancer and Fournier's gangrene - current knowledge and therapeutic options.

Authors:  Tomislav Bruketa; Matea Majerovic; Goran Augustin
Journal:  World J Gastroenterol       Date:  2015-08-14       Impact factor: 5.742

6.  Prognostic Factors for Fournier's Gangrene; A 10-year Experience in Southeastern Iran.

Authors:  Amene Sabzi Sarvestani; Mehdi Zamiri; Mehdi Sabouri
Journal:  Bull Emerg Trauma       Date:  2013-07

7.  Overview of different scoring systems in Fournier's Gangrene and assessment of prognostic factors.

Authors:  Ömer Gökhan Doluoğlu; Mehmet Ali Karagöz; Muhammet Fatih Kılınç; Tolga Karakan; Cem Nedim Yücetürk; Haşmet Sarıcı; Berat Cem Özgür; Muzaffer Eroğlu
Journal:  Turk J Urol       Date:  2016-09

8.  Prognostic factors and treatment outcomes for patients with Fournier's gangrene: a retrospective study.

Authors:  Kyung Sook Hong; Hee Jung Yi; Ryung-Ah Lee; Kwang Ho Kim; Soon Sup Chung
Journal:  Int Wound J       Date:  2017-09-25       Impact factor: 3.315

9.  Fournier's Gangrene after Open Hemorrhoidectomy without a Predisposing Factor: Report of a Case and Review of the Literature.

Authors:  Guldeniz Karadeniz Cakmak; Oktay Irkorucu; Bulent H Ucan; Kemal Karakaya
Journal:  Case Rep Gastroenterol       Date:  2009-05-15

Review 10.  Fournier's gangrene: A retrospective analysis of 26 cases in a Canadian hospital and literature review.

Authors:  Michael McCormack; Anne Sophie Valiquette; Salima Ismail
Journal:  Can Urol Assoc J       Date:  2015 May-Jun       Impact factor: 1.862

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