| Literature DB >> 12705860 |
Errol C Friedberg1, Paula L Fischhaber.
Abstract
In this issue of Cell, a study by Valerie Mizrahi and her colleagues suggests that a putative error-prone DNA polymerase encoded by the dnaE2 gene of Mycobacterium tuberculosis may bypass certain types of DNA base damage, generating mutations. This may be an important mechanism for generating drug-resistant strains of M. tuberculosis.Entities:
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Year: 2003 PMID： 12705860 DOI： 10.1016/s0092-8674(03)00275-7
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582