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Literature DB >> 12704647

Heat shock proteins and the pancreas.

Zoltán Rakonczay¹, Tamás Takács, Imre Boros, János Lonovics.

Abstract

Heat shock proteins (HSPs) are cytoprotective molecules that help to maintain the metabolic and structural integrity of cells. In this review, we briefly discuss the regulation and function of HSPs. The review focuses on the current knowledge of pancreatic HSP induction, the HSP level changes during acute pancreatitis, the potential effects of the pre- and co-induction of HSPs in experimental acute pancreatitis, and the mechanisms by which HSPs might mediate cellular protection. Copyright 2003 Wiley-Liss, Inc.

Entities: Disease Gene

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Year: 2003 PMID： 12704647 DOI： 10.1002/jcp.10268

Source DB: PubMed Journal: J Cell Physiol ISSN： 0021-9541 Impact factor: 6.384

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Cited

18 in total

Review 1. Recent insights into the cellular mechanisms of acute pancreatitis.

Authors: Laura I Cosen-Binker; Herbert Y Gaisano
Journal: Can J Gastroenterol Date: 2007-01 Impact factor: 3.522

2. Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis.

Authors: Peter C Konturek; Artur Dembinski; Zygmunt Warzecha; Grzegorz Burnat; Piotr Ceranowicz; Eckhart G Hahn; Marcin Dembinski; Romana Tomaszewska; Stanislaw J Konturek
Journal: World J Gastroenterol Date: 2005-10-28 Impact factor: 5.742

3. Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: involvement of cyclooxygenases and heat shock protein 70.

Authors: Zygmunt Warzecha; Artur Dembinski; Piotr Ceranowicz; Stanislaw-J Konturek; Marcin Dembinski; Wieslaw-W Pawlik; Romana Tomaszewska; Jerzy Stachura; Beata Kusnierz-Cabala; Jerzy-W Naskalski; Peter-C Konturek
Journal: World J Gastroenterol Date: 2005-10-14 Impact factor: 5.742

4. Evidence of multimeric forms of HSP70 with phosphorylation on serine and tyrosine residues--implications for roles of HSP70 in detection of GI cancers.

Authors: Anand Dutta; Mohit Girotra; Nipun Merchant; Padmanabhan Nair; Sudhir Kumar Dutta
Journal: Asian Pac J Cancer Prev Date: 2013

Review 5. Recent advances in the investigation of pancreatic inflammation induced by large doses of basic amino acids in rodents.

Authors: Balázs Kui; Zsolt Balla; Eszter T Végh; Petra Pallagi; Viktória Venglovecz; Béla Iványi; Tamás Takács; Péter Hegyi; Zoltán Rakonczay
Journal: Lab Invest Date: 2013-12-23 Impact factor: 5.662

10. Heat shock protein 70-2 and tumor necrosis factor-α gene polymorphisms in Chinese children with Henoch-Schönlein purpura.

Authors: Gui-Xia Ding; Chen-Hu Wang; Ruo-Chen Che; Wan-Zhen Guan; Yang-Gang Yuan; Min Su; Ai-Hua Zhang; Song-Ming Huang
Journal: World J Pediatr Date: 2015-11-07 Impact factor: 2.764

Heat shock proteins and the pancreas.

Review 1. Recent insights into the cellular mechanisms of acute pancreatitis.

2. Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis.

3. Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: involvement of cyclooxygenases and heat shock protein 70.

4. Evidence of multimeric forms of HSP70 with phosphorylation on serine and tyrosine residues--implications for roles of HSP70 in detection of GI cancers.

Review 5. Recent advances in the investigation of pancreatic inflammation induced by large doses of basic amino acids in rodents.

6. Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection.

7. Therapeutic proteasome inhibition in experimental acute pancreatitis.

8. Polymorphisms of the MCP-1 and HSP70-2 genes in Korean patients with alcoholic chronic pancreatitis.

Review 9. Acute pancreatitis: the stress factor.

10. Heat shock protein 70-2 and tumor necrosis factor-α gene polymorphisms in Chinese children with Henoch-Schönlein purpura.