| Literature DB >> 12704181 |
S Häussler1, M Rohde, N von Neuhoff, M Nimtz, I Steinmetz.
Abstract
In this study we report that extracellular Burkholderia pseudomallei rhamnolipid induced cytopathic changes characterized by retraction, rounding up, and, finally, detachment in phagocytic and nonphagocytic cell lines. These changes were due to a progressive reorganization of the F-actin network resulting in impaired cell cycle progression and a reduced phagocytic function of macrophages.Entities:
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Year: 2003 PMID: 12704181 PMCID: PMC153222 DOI: 10.1128/IAI.71.5.2970-2975.2003
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441