Literature DB >> 12704171

Th1 cell development induced by cysteine proteinases A and B in localized cutaneous leishmaniasis due to Leishmania guyanensis.

Hervé Pascalis1, Anne Lavergne, Eliane Bourreau, Ghislaine Prévot-Linguet, Amina Kariminia, Roger Pradinaud, Sima Rafati, Pascal Launois.   

Abstract

The cysteine proteinases CPA and CPB from Leishmania major induced Th1 responses in patients with leishmaniasis due to Leishmania guyanensis. Furthermore, cysteine proteinases induced neither interleukin 4 (IL-4) nor IL-13 and low levels of IL-10 in controls and patients. The results suggest that CPs would be quite good candidates for a vaccine against different Leishmania species.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12704171      PMCID： PMC153268          DOI： 10.1128/IAI.71.5.2924-2926.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  14 in total

1.  Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

Authors:  J C Mottram; A E Souza; J E Hutchison; R Carter; M J Frame; G H Coombs
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

2.  IFN-gamma-producing CD45RA+CD8+ and IL-10-producing CD45RA-CD4+ T cells generated in response to LACK in naive subjects never exposed to Leishmania.

Authors:  Eliane Bourreau; Marion Collet; Ghislaine Prévot; Geneviève Milon; Dominique Ashimoff; Hitoshi Hasagewa; Carlos Parra-Lopez; Pascal Launois
Journal:  Eur J Immunol       Date:  2002-02       Impact factor: 5.532

3.  The stage-regulated expression of Leishmania mexicana CPB cysteine proteases is mediated by an intercistronic sequence element.

Authors:  D R Brooks; H Denise; G D Westrop; G H Coombs; J C Mottram
Journal:  J Biol Chem       Date:  2001-10-09       Impact factor: 5.157

4.  MUST, a computer package of Management Utilities for Sequences and Trees.

Authors:  H Philippe
Journal:  Nucleic Acids Res       Date:  1993-11-11       Impact factor: 16.971

5.  Identification of Leishmania major cysteine proteinases as targets of the immune response in humans.

Authors:  S Rafati; A H Salmanian; K Hashemi; C Schaff; S Belli; N Fasel
Journal:  Mol Biochem Parasitol       Date:  2001-03       Impact factor: 1.759

6.  A Leishmania homologue of receptors for activated C-kinase (LACK) induces both interferon-gamma and interleukin-10 in natural killer cells of healthy blood donors.

Authors:  K Maasho; I Satti; S Nylén; G Guzman; F Koning; H Akuffo
Journal:  J Infect Dis       Date:  2000-07-24       Impact factor: 5.226

7.  LACK-specific CD4(+) T cells that induce gamma interferon production in patients with localized cutaneous leishmaniasis during an early stage of infection.

Authors:  Eliane Bourreau; Ghislaine Prévot; Jacques Gardon; Roger Pradinaud; Hitoshi Hasagewa; Geneviève Milon; Pascal Launois
Journal:  Infect Immun       Date:  2002-06       Impact factor: 3.441

8.  Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan.

Authors:  E A Khalil; A M El Hassan; E E Zijlstra; M M Mukhtar; H W Ghalib; B Musa; M E Ibrahim; A A Kamil; M Elsheikh; A Babiker; F Modabber
Journal:  Lancet       Date:  2000-11-04       Impact factor: 79.321

9.  A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major.

Authors:  S Rafati; A H Salmanian; T Taheri; M Vafa; N Fasel
Journal:  Vaccine       Date:  2001-05-14       Impact factor: 3.641

Review 10.  Interleukin-10.

Authors:  K W Moore; A O'Garra; R de Waal Malefyt; P Vieira; T R Mosmann
Journal:  Annu Rev Immunol       Date:  1993       Impact factor: 28.527
View more
  4 in total

Review 1.  Identifying vaccine targets for anti-leishmanial vaccine development.

Authors:  Shyam Sundar; Bhawana Singh
Journal:  Expert Rev Vaccines       Date:  2014-04       Impact factor: 5.217

2.  Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins.

Authors:  Maria Agallou; Evita Athanasiou; Olga Koutsoni; Eleni Dotsika; Evdokia Karagouni
Journal:  Front Immunol       Date:  2014-06-10       Impact factor: 7.561

3.  Liposomal Elongation Factor-1α Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis.

Authors:  Abdus Sabur; Sudipta Bhowmick; Rudra Chhajer; Sarfaraz Ahmad Ejazi; Nicky Didwania; Mohammad Asad; Anirban Bhattacharyya; Utsa Sinha; Nahid Ali
Journal:  Front Immunol       Date:  2018-01-30       Impact factor: 7.561

4.  Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine.

Authors:  Maria Agallou; Maritsa Margaroni; Evita Athanasiou; Dimitra K Toubanaki; Katerina Kontonikola; Konstantina Karidi; Olga Kammona; Costas Kiparissides; Evdokia Karagouni
Journal:  PLoS Negl Trop Dis       Date:  2017-01-23
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.