Literature DB >> 12702280

Metabolically engineered methylotrophic yeast cells and enzymes as sensor biorecognition elements.

Mykhailo Gonchar1, Mykola Maidan, Yaroslav Korpan, Volodymyr Sibirny, Zbigniew Kotylak, Andrei Sibirny.   

Abstract

An extended definition of the term metabolic engineering is given and its successful use in the construction of biorecognition elements of sensors is demonstrated. It is shown that genetic and chemical modifications of methylotrophic yeast cells provide directed changes in their physiological responses towards methanol, ethanol and formaldehyde resulting in enhanced selectivity and shorter time response of the corresponding potentiometric and amperometric biosensors.

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Year:  2002        PMID： 12702280     DOI： 10.1016/S1567-1356(02)00124-1

Source DB:  PubMed          Journal:  FEMS Yeast Res        ISSN： 1567-1356            Impact factor:   2.796


  5 in total

1.  Identification of the cadmium-inducible Hansenula polymorpha SEO1 gene promoter by transcriptome analysis and its application to whole-cell heavy-metal detection systems.

Authors:  Jeong-Nam Park; Min Jeong Sohn; Doo-Byoung Oh; Ohsuk Kwon; Sang Ki Rhee; Cheol-Goo Hur; Sang Yup Lee; Gerd Gellissen; Hyun Ah Kang
Journal:  Appl Environ Microbiol       Date:  2007-07-27       Impact factor: 4.792

2.  Construction of uricase-overproducing strains of Hansenula polymorpha and its application as biological recognition element in microbial urate biosensor.

Authors:  Kostyantyn V Dmytruk; Oleh V Smutok; Olena V Dmytruk; Wolfgang Schuhmann; Andriy A Sibirny
Journal:  BMC Biotechnol       Date:  2011-05-25       Impact factor: 2.563

3.  Regulation of methanol utilisation pathway genes in yeasts.

Authors:  Franz S Hartner; Anton Glieder
Journal:  Microb Cell Fact       Date:  2006-12-14       Impact factor: 5.328

4.  Bioconversion of airborne methylamine by immobilized recombinant amine oxidase from the thermotolerant yeast Hansenula polymorpha.

Authors:  Sasi Sigawi; Marina Nisnevitch; Oksana Zakalska; Andriy Zakalskiy; Yeshayahu Nitzan; Mykhailo Gonchar
Journal:  ScientificWorldJournal       Date:  2014-01-29

5.  Statistically Designed Medium Reveals Interactions between Metabolism and Genetic Information Processing for Production of Stable Human Serum Albumin in Pichia pastoris.

Authors:  Nitu Maity; Saroj Mishra
Journal:  Biomolecules       Date:  2019-10-04
  5 in total

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