Literature DB >> 12701781

Asymmetric medial degeneration of the ascending aorta in aortic valve disease: a pilot study of surgical management.

Maurizio Cotrufo1, Alessandro Della Corte, Luca S De Santo, Marisa De Feo, Franco E Covino, Giovanni Dialetto.   

Abstract

BACKGROUND AND AIM OF THE STUDY: In structural aortic valve disease, medial degeneration is often associated with ascending aorta dilatation. This pathology is often asymmetric, with more severe involvement of the convex aspect of the ascending aorta. The condition can be managed with surgical excision of the diseased portion of the aortic wall and remodeling reconstruction at the time of aortic valve replacement (AVR).
METHODS: Sixty-one patients underwent AVR and 'waistcoat aortoplasty'. Sinus dilatation was repaired by plicating the subcoronary redundant aortic wall using anchoring sutures of the valve prosthesis. The diseased aortic wall was removed via a triangular resection, and the aorta reconstructed with a double-layer technique, to achieve autologous reinforcement of the convex right posterolateral wall and stress reduction on the aortotomy suture line. Echocardiography was performed preoperatively, immediately postoperatively, and every six months thereafter. The significance of diameter variations was evaluated.
RESULTS: There was no hospital mortality, and only low postoperative morbidity. Post-reduction diameters at the sinuses, sinotubular junction and ascending aorta were significantly less than preoperative values (p < 0.0001). During a mean follow up of 33.8 +/- 10.2 months (range: 13-50 months), no significant increase in root (p = 0.32), sinotubular (p = 0.15), or ascending diameter (p = 0.11) was observed.
CONCLUSION: The 'waistcoat aortoplasty' should be considered when dealing with asymmetric ascending dilation secondary to aortic valve disease-related medial degeneration. However, additional studies with a longer follow up are needed to confirm these findings.

Entities:  

Mesh:

Year:  2003        PMID: 12701781

Source DB:  PubMed          Journal:  J Heart Valve Dis        ISSN: 0966-8519


  3 in total

1.  Ascending aorta dilatation in aortic valve disease: morphological analysis of medial changes.

Authors:  Lucio Agozzino; Pasquale Santè; Franca Ferraraccio; Marina Accardo; Marisa De Feo; Luca Salvatore De Santo; Gianantonio Nappi; Manuela Agozzino; Salvatore Esposito
Journal:  Heart Vessels       Date:  2006-07       Impact factor: 2.037

2.  Long-term follow-up of reduction ascending aortoplasty with autologous partial wrapping: for which patient is waistcoat aortoplasty best suited?

Authors:  Alessandro Della Corte; Marisa De Feo; Ciro Bancone; Raffaela Provenzano; Salvatore Giordano; Marianna Buonocore; Gianantonio Nappi; Maurizio Cotrufo
Journal:  Interact Cardiovasc Thorac Surg       Date:  2011-11-15

3.  Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy.

Authors:  Ali Fatehi Hassanabad; Alex J Barker; David Guzzardi; Michael Markl; Chris Malaisrie; Patrick M McCarthy; Paul W M Fedak
Journal:  Front Physiol       Date:  2017-07-10       Impact factor: 4.566

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.