Literature DB >> 12699088

Expression and potential function of Rho family small G proteins in cells of the mammalian seminiferous epithelium.

Edward A Freeman1, Purnima Jani, Clarke E Millette.   

Abstract

Dynamic cellular rearrangements involving the actin cytoskeleton are required of both Sertoli and germ cells during spermatogenesis. Rho family small G proteins have been implicated in the control of the actin cytoskeleton in numerous cell types. Therefore, RhoA and Rac1 were investigated in Sertoli and germ cells. RhoA and Rac1 have been detected at both the mRNA and protein levels in these cells. In addition, Sertoli cell L-selectin is shown to interact with actin binding proteins, potentially providing a link between L-selectin and Rac1 signaling. Finally, inactivation of Sertoli cell Rho family proteins yields disruption of the actin cytoskeleton.

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Year:  2002        PMID： 12699088     DOI： 10.1080/15419060216016

Source DB:  PubMed          Journal:  Cell Commun Adhes        ISSN： 1543-5180


  7 in total

1.  Analysis of RhoE expression in the testis, epididymis and ductus deferens, and the effects of its deficiency in mice.

Authors:  Olga Gómez; Begoña Ballester-Lurbe; Rosa M Guasch; Ignacio Pérez-Roger; Empar García-Roselló; José Terrado
Journal:  J Anat       Date:  2014-10-01       Impact factor: 2.610

2.  Immunohistological profile of the Ras homologous B protein (RhoB) in human testes showing normal spermatogenesis, spermatogenic arrest and Sertoli cell only syndrome.

Authors:  Mohamed A Adly; Mahmoud Rezk Abdelwahed Hussein
Journal:  Pathol Oncol Res       Date:  2009-12-08       Impact factor: 3.201

3.  Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization-A Study Using the Adjudin Model.

Authors:  Linxi Li; Elizabeth I Tang; Haiqi Chen; Qingquan Lian; Renshan Ge; Bruno Silvestrini; C Yan Cheng
Journal:  Endocrinology       Date:  2017-12-01       Impact factor: 4.736

4.  PKA-dependent phosphorylation of LIMK1 and Cofilin is essential for mouse sperm acrosomal exocytosis.

Authors:  Ana Romarowski; María A Battistone; Florenza A La Spina; Lis del C Puga Molina; Guillermina M Luque; Alejandra M Vitale; Patricia S Cuasnicu; Pablo E Visconti; Darío Krapf; Mariano G Buffone
Journal:  Dev Biol       Date:  2015-07-10       Impact factor: 3.582

5.  A novel testis-specific GTPase serves as a link to proteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis.

Authors:  Ning Zhang; Junbo Liang; Yongqiang Tian; Ligang Yuan; Lan Wu; Shiying Miao; Shudong Zong; Linfang Wang
Journal:  Mol Biol Cell       Date:  2010-10-27       Impact factor: 4.138

6.  p70 S6 kinase and actin dynamics: A perspective.

Authors:  Carman K M Ip; Alice S T Wong
Journal:  Spermatogenesis       Date:  2012-01-01

Review 7.  A head-to-tail view of L-selectin and its impact on neutrophil behaviour.

Authors:  Aleksandar Ivetic
Journal:  Cell Tissue Res       Date:  2018-01-20       Impact factor: 5.249
  7 in total

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