Literature DB >> 12698275

Aspergillus niger citric acid accumulation: do we understand this well working black box?

Levente Karaffa1, Christian P Kubicek.   

Abstract

This Mini-Review summarizes the current knowledge on the biochemical and physiological events leading to massive citric acid accumulation by Aspergillus niger under industrially comparable conditions, thereby particularly emphasizing the roles of glycolytic flux and its control, excretion of citric acid from the mitochondria and the cytosol, and the critical fermentation variables. The potential of novel techniques for metabolic analysis and genomic approaches in understanding this fermentation is also discussed.

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Year:  2003        PMID： 12698275     DOI： 10.1007/s00253-002-1201-7

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN： 0175-7598            Impact factor:   4.813


  49 in total

1.  Firing range soils yield a diverse array of fungal isolates capable of organic acid production and Pb mineral solubilization.

Authors:  Tarah S Sullivan; Neil R Gottel; Nicholas Basta; Philip M Jardine; Christopher W Schadt
Journal:  Appl Environ Microbiol       Date:  2012-06-22       Impact factor: 4.792

2.  A mutation of Aspergillus niger for hyper-production of citric acid from corn meal hydrolysate in a bioreactor.

Authors:  Wei Hu; Jing Liu; Ji-hong Chen; Shu-yang Wang; Dong Lu; Qing-hua Wu; Wen-jian Li
Journal:  J Zhejiang Univ Sci B       Date:  2014-11       Impact factor: 3.066

3.  Cloning and Characterization of a Pyruvate Carboxylase Gene from Penicillium rubens and Overexpression of the Genein the Yeast Yarrowia lipolytica for Enhanced Citric Acid Production.

Authors:  Ge-Yi Fu; Yi Lu; Zhe Chi; Guang-Lei Liu; Shou-Feng Zhao; Hong Jiang; Zhen-Ming Chi
Journal:  Mar Biotechnol (NY)       Date:  2016-02       Impact factor: 3.619

4.  Mitochondrial Citrate Transporters CtpA and YhmA Are Required for Extracellular Citric Acid Accumulation and Contribute to Cytosolic Acetyl Coenzyme A Generation in Aspergillus luchuensis mut. kawachii.

Authors:  Chihiro Kadooka; Kosuke Izumitsu; Masahira Onoue; Kayu Okutsu; Yumiko Yoshizaki; Kazunori Takamine; Masatoshi Goto; Hisanori Tamaki; Taiki Futagami
Journal:  Appl Environ Microbiol       Date:  2019-04-04       Impact factor: 4.792

Review 5.  Biosynthesis of some organic acids and lipids in industrially important microorganisms is promoted by pyruvate carboxylases.

Authors:  Shou-Feng Zhao; Zhe Chi; Guang-Lei Liu; Zhong Hu; Long-Fei Wu; Zhen-Ming Chi
Journal:  J Biosci       Date:  2019-06       Impact factor: 1.826

6.  Mapping N-linked glycosylation sites in the secretome and whole cells of Aspergillus niger using hydrazide chemistry and mass spectrometry.

Authors:  Lu Wang; Uma K Aryal; Ziyu Dai; Alisa C Mason; Matthew E Monroe; Zhi-Xin Tian; Jian-Ying Zhou; Dian Su; Karl K Weitz; Tao Liu; David G Camp; Richard D Smith; Scott E Baker; Wei-Jun Qian
Journal:  J Proteome Res       Date:  2011-12-02       Impact factor: 4.466

7.  Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88.

Authors:  Mikael R Andersen; Margarita P Salazar; Peter J Schaap; Peter J I van de Vondervoort; David Culley; Jette Thykaer; Jens C Frisvad; Kristian F Nielsen; Richard Albang; Kaj Albermann; Randy M Berka; Gerhard H Braus; Susanna A Braus-Stromeyer; Luis M Corrochano; Ziyu Dai; Piet W M van Dijck; Gerald Hofmann; Linda L Lasure; Jon K Magnuson; Hildegard Menke; Martin Meijer; Susan L Meijer; Jakob B Nielsen; Michael L Nielsen; Albert J J van Ooyen; Herman J Pel; Lars Poulsen; Rob A Samson; Hein Stam; Adrian Tsang; Johannes M van den Brink; Alex Atkins; Andrea Aerts; Harris Shapiro; Jasmyn Pangilinan; Asaf Salamov; Yigong Lou; Erika Lindquist; Susan Lucas; Jane Grimwood; Igor V Grigoriev; Christian P Kubicek; Diego Martinez; Noël N M E van Peij; Johannes A Roubos; Jens Nielsen; Scott E Baker
Journal:  Genome Res       Date:  2011-05-04       Impact factor: 9.043

8.  Posttranslational modification of 6-phosphofructo-1-kinase in Aspergillus niger.

Authors:  Suzana Mesojednik; Matic Legisa
Journal:  Appl Environ Microbiol       Date:  2005-03       Impact factor: 4.792

9.  Regulation of alternative oxidase at the transcription stage in Aspergillus niger under the conditions of citric acid production.

Authors:  Takasumi Hattori; Kuniki Kino; Kohtaro Kirimura
Journal:  Curr Microbiol       Date:  2009-02-12       Impact factor: 2.188

10.  Systemic analysis of the response of Aspergillus niger to ambient pH.

Authors:  Mikael R Andersen; Linda Lehmann; Jens Nielsen
Journal:  Genome Biol       Date:  2009-05-01       Impact factor: 13.583
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