Literature DB >> 12696732

Value of core needle biopsy in the diagnosis of soft tissue tumours.

V P Madhavan1, S Robinson Smile, S Sarath Chandra, C Ratnakar.   

Abstract

We performed a prospective study to determine the accuracy of core needle biopsy in the diagnosis and grading of soft tissue tumours and to study the morbidity of core needle biopsy. Forty one cases of soft tissue tumours, 24 of them malignant and 17 benign, were biopsied with an 18G core needle. Core needle biopsy reports were compared with the final histopathological report after definitive procedure or incisional biopsy. 85.3% of core biopsies yielded adequate sample. Core needle biopsy had a sensitivity of 90%, specificity of 100%, positive predictive value of 100% and a negative predictive value of 88.23%. Overall accuracy for diagnosis of malignancy was 94.28%, 77.7% of tumours were correctly subtyped and none of them were histologically graded. There was no immediate complication of haemorrhage in any of the cases. Thus, we conclude that core needle biopsy is equivalent to incisional biopsy in diagnostic accuracy and being simple, less expensive and unlikely to compromise further management, can be used in place of open biopsy of soft tissue tumours.

Entities:  

Mesh:

Year:  2002        PMID: 12696732

Source DB:  PubMed          Journal:  Indian J Pathol Microbiol        ISSN: 0377-4929            Impact factor:   0.740


  5 in total

Review 1.  Image-guided percutaneous spinal biopsy.

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Journal:  Skeletal Radiol       Date:  2012-06-04       Impact factor: 2.199

2.  Initial CT-guided percutaneous biopsy of vertebral lesions: Evaluation of its diagnostic accuracy and clinical value.

Authors:  Wen-Bin Hua; Qiang Wu; Bo Zhang; Shu-Hua Yang; Zeng-Wu Shao; Wei-Hua Xu; Ye Wang; Xu-Dong Zhang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2015-07-31

3.  Percutaneous CT-guided biopsy of the spine: results of 430 biopsies.

Authors:  Eugenio Rimondi; Eric L Staals; Costantino Errani; Giuseppe Bianchi; Roberto Casadei; Marco Alberghini; Maria Cristina Malaguti; Giuseppe Rossi; Stefano Durante; Mario Mercuri
Journal:  Eur Spine J       Date:  2008-05-08       Impact factor: 3.134

4.  Preoperative Biopsy in Patients with Retroperitoneal Sarcoma: Usage and Outcomes in a National Cohort.

Authors:  Richard J Straker; Yun Song; Adrienne B Shannon; Clayton T Marcinak; John T Miura; Douglas L Fraker; Giorgos C Karakousis
Journal:  Ann Surg Oncol       Date:  2021-02-16       Impact factor: 5.344

Review 5.  Biopsy of soft tissue masses: evidence-based medicine for the musculoskeletal tumor society.

Authors:  Bruce T Rougraff; Albert Aboulafia; J Sybil Biermann; John Healey
Journal:  Clin Orthop Relat Res       Date:  2009-07-14       Impact factor: 4.176

  5 in total

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