Literature DB >> 1269649

The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide.

C J Hayes, J D Palmer.   

Abstract

The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a retilinear one with up to 70% reduction in activity with the administration of 25% heavy water.

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Year:  1976        PMID： 1269649     DOI： 10.1007/BF01920801

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Course of deuteriation and some physiological effects of deuterium in mice.

Authors:  J J KATZ; H L CRESPI; D M CZAJKA; A J FINKEL
Journal:  Am J Physiol       Date:  1962-11

2.  Effect of heavy water on different types of muscle and on glycerol-extracted psoas fibres.

Authors:  B KAMINER
Journal:  Nature       Date:  1960-01-16       Impact factor: 49.962

3.  Some observations on biological effects of deuterium, with special reference to effects on neoplastic processes.

Authors:  J J KATZ; H L CRESPI; R J HASTERLIK; J F THOMSON; A J FINKEL
Journal:  J Natl Cancer Inst       Date:  1957-05       Impact factor: 13.506

4.  The effect of deuterium oxide (heavy water) on conduction velocity in isolated frog nerve.

Authors:  L GARBY; P NORDQVIST
Journal:  Acta Physiol Scand       Date:  1955-10-27

5.  The chronomutagenic effect of deuterium oxide on the period and entrainment of a biological rhythm.

Authors:  H B Dowse; J D Palmer
Journal:  Biol Bull       Date:  1972-12       Impact factor: 1.818

6.  Entrainment of circadian activity rhythms in mice by electrostatic fields.

Authors:  H B Dowse; J D Palmer
Journal:  Nature       Date:  1969-05-10       Impact factor: 49.962

7.  Effect of deuterium oxide on the relaxation of glycerol-extracted muscle.

Authors:  B Kaminer
Journal:  Nature       Date:  1966-02-19       Impact factor: 49.962

8.  The Basis of the Pharmacological Action of Heavy Water in Mammals.

Authors:  H G Barbour
Journal:  Yale J Biol Med       Date:  1937-07
  8 in total
  1 in total

1.  Deuterium nuclear magnetic resonance measurements of blood flow and tissue perfusion employing 2H2O as a freely diffusible tracer.

Authors:  J J Ackerman; C S Ewy; N N Becker; R A Shalwitz
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205
  1 in total

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