Literature DB >> 1269637

Direct fluorination of carcinogenic polycylic aromatic hydrocarbons. 6-Fluorobenzo(a)pyrene.

I Agranat, M Rabinovitz, H Selig, C H Lin.   

Abstract

Xenon difluoride reacts with benzo[a]pyrene(BaP) in dichloromethane solution in an open system to give 6-fluorobenzo[a]pyrene. This method constitutes a direct route to fluorine substituted carcinogenic polycyclic aromatic hydrocarbons.

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Year:  1976        PMID： 1269637     DOI： 10.1007/BF01920768

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  3 in total

1.  The carcinogenicity of fluoro derivatives of 10-methyl-1,2-benzanthracene. I. 3- and 4'-Monofluoro derivatives.

Authors:  E C MILLER; J A MILLER
Journal:  Cancer Res       Date:  1960-01       Impact factor: 12.701

Review 2.  Epoxides in polycyclic aromatic hydrocarbon metabolism and carcinogenesis.

Authors:  P Sims; P L Grover
Journal:  Adv Cancer Res       Date:  1974       Impact factor: 6.242

3.  Induced nucleophilic substitution in benzo(a)pyrene.

Authors:  M D Johnson; M Calvin
Journal:  Nature       Date:  1973-01-26       Impact factor: 49.962
  3 in total

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