Literature DB >> 12695662

Yeast POL5 is an evolutionarily conserved regulator of rDNA transcription unrelated to any known DNA polymerases.

Wei Yang1, Igor B Rogozin, Eugene V Koonin.   

Abstract

We show that yeast protein Yel055cp, which has been identified as the fifth essential DNA polymerase in Saccharomyces cerevisiae (POL5), is a member of a family of predicted rDNA transcription regulators (typified by human MYB-binding protein MYBBP1 A), which are represented by a single ortholog in all animals, fungi and plants with sequenced genomes. These proteins are confidently predicted to have an entirely a-helical structure and are unrelated to the B class DNA polymerases, as claimed for yeast POL5, or any other known polymerases.

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Year:  2003        PMID： 12695662     DOI： 10.4161/cc.2.2.329

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  9 in total

1.  Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA.

Authors:  Julia Hochstatter; Michael Hölzel; Michaela Rohrmoser; Lothar Schermelleh; Heinrich Leonhardt; Rebecca Keough; Thomas J Gonda; Axel Imhof; Dirk Eick; Gernot Längst; Attila Németh
Journal:  J Biol Chem       Date:  2012-05-29       Impact factor: 5.157

2.  Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase.

Authors:  Claudia Perrera; Riccardo Colombo; Barbara Valsasina; Patrizia Carpinelli; Sonia Troiani; Michele Modugno; Laura Gianellini; Paolo Cappella; Antonella Isacchi; Jurgen Moll; Luisa Rusconi
Journal:  J Biol Chem       Date:  2010-02-22       Impact factor: 5.157

3.  Isw1 acts independently of the Isw1a and Isw1b complexes in regulating transcriptional silencing at the ribosomal DNA locus in Saccharomyces cerevisiae.

Authors:  John E Mueller; Mary Bryk
Journal:  J Mol Biol       Date:  2007-05-18       Impact factor: 5.469

4.  Pol5p, a novel binding partner to Cdc10p in fission yeast involved in rRNA production.

Authors:  Farzana Khaliq Nadeem; Derek Blair; Christopher J McInerny
Journal:  Mol Genet Genomics       Date:  2006-07-01       Impact factor: 3.291

5.  Proteins and RNA sequences required for the transition of the t-Utp complex into the SSU processome.

Authors:  Jennifer E G Gallagher
Journal:  FEMS Yeast Res       Date:  2019-01-01       Impact factor: 2.796

6.  Rrp14 controls rRNA transcription via facilitating the translocation of Pol5 into the nucleolus.

Authors:  Zhen Lin; Haiyan Liu; Hongzhi Chen; Hongshi Cao; Xiaochang Liu; Haichao Zhu; Lu Zhao; Zhiming Chen
Journal:  Cell Cycle       Date:  2022-01-02       Impact factor: 4.534

7.  Epigeneitc silencing of ribosomal RNA genes by Mybbp1a.

Authors:  Bertrand Chin-Ming Tan; Chang-Ching Yang; Chia-Ling Hsieh; Yin-Hsiang Chou; Chang-Zheng Zhong; Benjamin Yat-Ming Yung; Hsuan Liu
Journal:  J Biomed Sci       Date:  2012-06-11       Impact factor: 8.410

8.  Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae.

Authors:  Ana Ramos-Sáenz; Daniel González-Álvarez; Olga Rodríguez-Galán; Alfonso Rodríguez-Gil; Sonia G Gaspar; Eduardo Villalobo; Mercedes Dosil; Jesús de la Cruz
Journal:  RNA       Date:  2019-08-14       Impact factor: 4.942

9.  Pol5 is required for recycling of small subunit biogenesis factors and for formation of the peptide exit tunnel of the large ribosomal subunit.

Authors:  Christina M Braun; Philipp Hackert; Catharina E Schmid; Markus T Bohnsack; Katherine E Bohnsack; Jorge Perez-Fernandez
Journal:  Nucleic Acids Res       Date:  2020-01-10       Impact factor: 16.971
  9 in total

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