Literature DB >> 12695385

Risks and benefits of hormone replacement therapy: the evidence speaks.

Karin H Humphries1, Sabrina Gill.   

Abstract

Until recently, observational studies suggested a decreased risk of cardiovascular disease, osteoporotic fractures, cognitive decline and colon cancer with the use of hormone replacement therapy (HRT). Recent randomized controlled trials have failed to show a protective effect of HRT in reducing the risk of coronary artery disease and instead have revealed an increased risk of heart disease, stroke, invasive breast cancer and venous thromboembolism, but a decreased risk of colorectal cancer and osteoporotic fractures. In this article we review the current evidence of the risks and benefits of HRT.

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Year:  2003        PMID： 12695385      PMCID： PMC152685     

Source DB:  PubMed          Journal:  CMAJ        ISSN： 0820-3946            Impact factor:   8.262


  103 in total

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Journal:  JAMA       Date:  2001-03-21       Impact factor: 56.272

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  16 in total

1.  Combination hormone replacement therapy and dementia.

Authors:  Eric Wooltorton
Journal:  CMAJ       Date:  2003-07-22       Impact factor: 8.262

2.  [Frederick Banting and the opportunities for research for general practitioners].

Authors:  Iona Heath
Journal:  CMAJ       Date:  2011-05-02       Impact factor: 8.262

3.  Frederick Banting and the opportunities of research by general practitioners.

Authors:  Iona Heath
Journal:  CMAJ       Date:  2011-03-28       Impact factor: 8.262

4.  Estrogen prevents sustained COLO-205 human colon cancer cell growth by inducing apoptosis, decreasing c-myb protein, and decreasing transcription of the anti-apoptotic protein bcl-2.

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Journal:  Tumour Biol       Date:  2009-12-18

5.  Modulatory role of genistein on placenta and maternal bone minerals composition: further insight into its influence on pregnancy and foetal development.

Authors:  Titilola Aderonke Samuel; Funmileyi Olubajo Awobajo; Taiwo Hafsah Akinsanya; Habeeb Shemilore Oyediran; Ikechukwu Eric Egege; Chiamaka Blessing Egede; Bukola Oluwasegun Timothy
Journal:  Biol Futur       Date:  2020-06-25

6.  Treatment with qibaomeiran, a kidney-invigorating Chinese herbal formula, antagonizes estrogen decline in ovariectomized rats.

Authors:  Ying Xu; Xiao-ping Ma; Jie Ding; Zhen-li Liu; Zhi-qian Song; Hong-ning Liu; Na Lin
Journal:  Rejuvenation Res       Date:  2014-08       Impact factor: 4.663

7.  Effect of hormone replacement therapy (HRT) on periodontal status of postmenopausal women.

Authors:  Giuseppe Pizzo; Rosario Guiglia; Maria E Licata; Ignazio Pizzo; Joan M Davis; Giovanna Giuliana
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8.  Colorectal cancer: a case control study of dietary factors, king faisal specialist hospital and researh center, riyadh, saudi arabia.

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Journal:  J Family Community Med       Date:  2008-05

9.  Estrogenic activities of Fatty acids and a sterol isolated from royal jelly.

Authors:  Kazu-Michi Suzuki; Yoichiro Isohama; Hiroe Maruyama; Yayoi Yamada; Yukio Narita; Shozo Ohta; Yoko Araki; Takeshi Miyata; Satoshi Mishima
Journal:  Evid Based Complement Alternat Med       Date:  2008-09       Impact factor: 2.629

10.  Long-term efficacy and safety of anastrozole for adjuvant treatment of early breast cancer in postmenopausal women.

Authors:  Sharath Gangadhara; Gianfilippo Bertelli
Journal:  Ther Clin Risk Manag       Date:  2009-05-04       Impact factor: 2.423
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