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Literature DB >> 12692040

Changing genes; losing lactase.

R J Grand¹, R K Montgomery, D K Chitkara, J N Hirschhorn.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2003 PMID： 12692040 PMCID： PMC1773627 DOI： 10.1136/gut.52.5.617

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

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23 in total

1. Lactase haplotype diversity in the Old World.

Authors: E J Hollox; M Poulter; M Zvarik; V Ferak; A Krause; T Jenkins; N Saha; A I Kozlov; D M Swallow
Journal: Am J Hum Genet Date: 2000-11-28 Impact factor: 11.025

2. Development of the human gastrointestinal tract. A review.

Authors: R J Grand; J B Watkins; F M Torti
Journal: Gastroenterology Date: 1976-05 Impact factor: 22.682

Review 3. Genetics of lactose digestion in humans.

Authors: G Flatz
Journal: Adv Hum Genet Date: 1987

4. The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation.

Authors: R Fang; N A Santiago; L C Olds; E Sibley
Journal: Gastroenterology Date: 2000-01 Impact factor: 22.682

5. Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.

Authors: S D Krasinski; H M Van Wering; M R Tannemaat; R J Grand
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2001-07 Impact factor: 4.052

6. Distribution of disaccharidase activity in the small bowel of normal and lactase-deficient subjects.

Authors: A D Newcomer; D B McGill
Journal: Gastroenterology Date: 1966-10 Impact factor: 22.682

7. Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene.

Authors: C Mitchelmore; J T Troelsen; N Spodsberg; H Sjöström; O Norén
Journal: Biochem J Date: 2000-03-01 Impact factor: 3.857

8. The biosynthetic basis of adult lactase deficiency.

Authors: J Witte; M Lloyd; V Lorenzsonn; H Korsmo; W Olsen
Journal: J Clin Invest Date: 1990-10 Impact factor: 14.808

9. Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase.

Authors: W Boll; P Wagner; N Mantei
Journal: Am J Hum Genet Date: 1991-05 Impact factor: 11.025

10. Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme.

Authors: N Mantei; M Villa; T Enzler; H Wacker; W Boll; P James; W Hunziker; G Semenza
Journal: EMBO J Date: 1988-09 Impact factor: 11.598

8 in total

1. Genetic signatures of strong recent positive selection at the lactase gene.

Authors: Todd Bersaglieri; Pardis C Sabeti; Nick Patterson; Trisha Vanderploeg; Steve F Schaffner; Jared A Drake; Matthew Rhodes; David E Reich; Joel N Hirschhorn
Journal: Am J Hum Genet Date: 2004-04-26 Impact factor: 11.025

2. Theodore E. Woodward Award: lactase persistence SNPs in African populations regulate promoter activity in intestinal cell culture.

Authors: Eric Sibley; Jong Kun Ahn
Journal: Trans Am Clin Climatol Assoc Date: 2011

3. Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5' flanking sequence.

Authors: Nana Yaa Baffour-Awuah; Eveline Delemarre; Yuko Fujiwara; Jarom Heijmans; David Boerwinkel; Selma Algra; John J Fialkovich; Shabana Islam; Tjalling Bosse; Richard J Grand; Stephen D Krasinski; Robert K Montgomery
Journal: Dig Dis Sci Date: 2010-11-18 Impact factor: 3.199

8. A double-blind, 377-subject randomized study identifies Ruminococcus, Coprococcus, Christensenella, and Collinsella as long-term potential key players in the modulation of the gut microbiome of lactose intolerant individuals by galacto-oligosaccharides.

Authors: M A Azcarate-Peril; J Roach; A Marsh; William D Chey; William J Sandborn; Andrew J Ritter; Dennis A Savaiano; T R Klaenhammer
Journal: Gut Microbes Date: 2021 Jan-Dec