| Literature DB >> 12690451 |
Abstract
We have analysed the expression, during embryogenesis, of a Drosophila gene asrij (Sanskrit; asR ij = blood), which encodes a novel conserved protein with putative transmembrane domains. asrij is expressed in the pole cells, amnioserosa, trachea and hemocytes. Embryos homozygous for a chromosomal deficiency that removes asrij have no embryonic hemocytes. Expression in the blood-cell lineage precedes that of known hematopoietic transcription factors. These results suggest that Drosophila asrij functions in the hematopoietic lineage.Entities:
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Year: 2003 PMID: 12690451 DOI: 10.1007/s00427-003-0305-0
Source DB: PubMed Journal: Dev Genes Evol ISSN: 0949-944X Impact factor: 0.900