Literature DB >> 12689582

All roads lead to ATF4.

D Thomas Rutkowski1, Randal J Kaufman.   

Abstract

Multiple intracellular stress pathways converge on a single event--phosphorylation of the translation initiation factor eIF2alpha and subsequent translational activation of the transcription factor ATF4. Exploring the consequences of this event has highlighted the ways in which stress is sensed and responded to via many distinct pathways.

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Year:  2003        PMID: 12689582     DOI: 10.1016/s1534-5807(03)00100-x

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  71 in total

1.  Knockdown of transmembrane protein 132A by RNA interference facilitates serum starvation-induced cell death in Neuro2a cells.

Authors:  Kentaro Oh-hashi; Kazuhide Imai; Hisashi Koga; Yoko Hirata; Kazutoshi Kiuchi
Journal:  Mol Cell Biochem       Date:  2010-05-09       Impact factor: 3.396

2.  Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response.

Authors:  Tomoko Kawai; Jinshui Fan; Krystyna Mazan-Mamczarz; Myriam Gorospe
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272

3.  Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells.

Authors:  Kentaro Oh-Hashi; Nao Irie; Takayuki Sakai; Kensuke Okuda; Hideko Nagasawa; Yoko Hirata; Kazutoshi Kiuchi
Journal:  Mol Cell Biochem       Date:  2016-07-08       Impact factor: 3.396

4.  Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington's disease.

Authors:  Juan I Sbodio; Solomon H Snyder; Bindu D Paul
Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-09       Impact factor: 11.205

5.  Reovirus induces and benefits from an integrated cellular stress response.

Authors:  Jennifer A Smith; Stephen C Schmechel; Arvind Raghavan; Michelle Abelson; Cavan Reilly; Michael G Katze; Randal J Kaufman; Paul R Bohjanen; Leslie A Schiff
Journal:  J Virol       Date:  2006-02       Impact factor: 5.103

Review 6.  Stress, inflammation, and defense of homeostasis.

Authors:  Raj Chovatiya; Ruslan Medzhitov
Journal:  Mol Cell       Date:  2014-04-24       Impact factor: 17.970

7.  eIF2α phosphorylation controls thermal nociception.

Authors:  Arkady Khoutorsky; Robert E Sorge; Masha Prager-Khoutorsky; Sophie Anne Pawlowski; Geraldine Longo; Seyed Mehdi Jafarnejad; Soroush Tahmasebi; Loren J Martin; Mark H Pitcher; Christos G Gkogkas; Reza Sharif-Naeini; Alfredo Ribeiro-da-Silva; Charles W Bourque; Fernando Cervero; Jeffrey S Mogil; Nahum Sonenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-03       Impact factor: 11.205

8.  Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.

Authors:  Weiguang Wang; Na Lian; Lingzhen Li; Heather E Moss; Weixi Wang; Daniel S Perrien; Florent Elefteriou; Xiangli Yang
Journal:  Development       Date:  2009-11-11       Impact factor: 6.868

9.  ATF4 is directly recruited by TLR4 signaling and positively regulates TLR4-trigged cytokine production in human monocytes.

Authors:  Chunyan Zhang; Nan Bai; Antao Chang; Zhuhong Zhang; Jing Yin; Wenzhi Shen; Yaping Tian; Rong Xiang; Chenghu Liu
Journal:  Cell Mol Immunol       Date:  2012-12-17       Impact factor: 11.530

10.  Transcriptional and post-translational regulation of mouse cation transport regulator homolog 1.

Authors:  Kentaro Oh-Hashi; Yuki Nomura; Kiyo Shimada; Hisashi Koga; Yoko Hirata; Kazutoshi Kiuchi
Journal:  Mol Cell Biochem       Date:  2013-04-25       Impact factor: 3.396

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