Literature DB >> 12686768

Spontaneous resolution of calvarial eosinophilic granuloma in children.

Marcelo Oliveira1, Paul Steinbok, John Wu, Navraj Heran, Douglas Cochrane.   

Abstract

OBJECTIVE: The recommended treatment for solitary calvarial eosinophilic granuloma (EG) is surgical resection by curettage, craniectomy or craniotomy. The purpose of this study was to describe the spontaneous resolution of calvarial EG and discuss 'observation only' as an option in the management of this condition.
METHODS: A retrospective review was performed of children with calvarial EG seen at a tertiary care children's hospital. Of a total of 17 such patients, four were managed without any intervention and formed the basis of this report.
RESULTS: In all four patients treated by 'observation only', there was a tender calvarial mass which enlarged rapidly over a few days and then resolved slowly over many weeks. The diagnosis of EG was based on the findings of plain radiographs and/or computed tomography. All masses had resolved by 8 weeks, and the underlying cranial defect filled in spontaneously in all cases. There was no recurrence at follow-up, which ranged from 2 months to 7 years.
CONCLUSIONS: 'Observation only' should be considered as a viable option in the management of children with solitary calvarial masses that have the radiographic features of EG. Consideration should be given to delaying surgical intervention to allow time to see if spontaneous resolution occurs. Copyright 2003 S. Karger AG, Basel

Entities:  

Mesh:

Year:  2003        PMID: 12686768     DOI: 10.1159/000069828

Source DB:  PubMed          Journal:  Pediatr Neurosurg        ISSN: 1016-2291            Impact factor:   1.162


  9 in total

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2.  Eosinophilic granuloma of the skull associated with epidural haematoma: a case report and review of the literature.

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Journal:  Childs Nerv Syst       Date:  2004-10       Impact factor: 1.475

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5.  Skull fracture mimicking eosinophilic granuloma.

Authors:  Todd Hollon; Paul E McKeever; Hugh J L Garton; Cormac O Maher
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6.  Langerhans cell histiocytosis with seborrheic eczema of the scalp and extensive calvarial involvement.

Authors:  Satoshi Tsutsumi; Shintaro Nakajima; Hisayuki Oda; Yukimasa Yasumoto
Journal:  Childs Nerv Syst       Date:  2016-01-27       Impact factor: 1.475

7.  Solitary Langerhans cell histocytosis of skull and spine in pediatric and adult patients.

Authors:  Seul-Kee Lee; Tae-Young Jung; Shin Jung; Dong-Kyun Han; Jung-Kil Lee; Hee-Jo Baek
Journal:  Childs Nerv Syst       Date:  2013-06-19       Impact factor: 1.475

8.  Disappearing lytic lesion of skull.

Authors:  Senthil Kumar Aiyappan; Upasana Ranga; Benjamin M Sagayaraj; Saveetha Veeraiyan
Journal:  J Neurosci Rural Pract       Date:  2015 Apr-Jun

9.  Eosinophilic granuloma/Langerhans cell histiocytosis: Pediatric neurosurgery update.

Authors:  Sandi Lam; Gaddum D Reddy; Rory Mayer; Yimo Lin; Andrew Jea
Journal:  Surg Neurol Int       Date:  2015-10-07
  9 in total

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