Literature DB >> 12686445

Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis) root extracts.

M I Alam1, A Gomes.   

Abstract

The methanolic root extracts of Vitex negundo Linn. and Emblica officinalis Gaertn. were explored for the first time for antisnake venom activity. The plant (V. negundo and E. officinalis) extracts significantly antagonized the Vipera russellii and Naja kaouthia venom induced lethal activity both in in vitro and in vivo studies. V. russellii venom-induced haemorrhage, coagulant, defibrinogenating and inflammatory activity was significantly neutralized by both plant extracts. No precipitating bands were observed between the plant extract and snake venom. The above observations confirmed that the plant extracts possess potent snake venom neutralizing capacity and need further investigation.

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Year:  2003        PMID： 12686445     DOI： 10.1016/s0378-8741(03)00049-7

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  32 in total

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Journal:  World J Gastroenterol       Date:  2008-06-21       Impact factor: 5.742

Review 3.  Vitex negundo and its medicinal value.

Authors:  Balraj Singh Gill; Richa Mehra; Sanjeev Kumar
Journal:  Mol Biol Rep       Date:  2018-10-11       Impact factor: 2.316

4.  Antivenom potential of ethanolic extract of Cordia macleodii bark against Naja venom.

Authors:  Pranay Soni; Surendra H Bodakhe
Journal:  Asian Pac J Trop Biomed       Date:  2014-05

5.  In silico identification of viper phospholipaseA2 inhibitors: validation by in vitro, in vivo studies.

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6.  Experimental validation of Vitex negundo leaves hydroalcoholic extract for neuroprotection in haloperidol induced parkinson's disease in rat.

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7.  Vitexins, nature-derived lignan compounds, induce apoptosis and suppress tumor growth.

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8.  Indigenous knowledge of medicinal plants used by Saperas community of Khetawas, Jhajjar District, Haryana, India.

Authors:  Manju Panghal; Vedpriya Arya; Sanjay Yadav; Sunil Kumar; Jaya Parkash Yadav
Journal:  J Ethnobiol Ethnomed       Date:  2010-01-28       Impact factor: 2.733

9.  Partial in vitro and in vivo red scorpion venom neutralization activity of Andrographis paniculata.

Authors:  Ranjana I Brahmane; Swanand S Pathak; Vikrant V Wanmali; Kartik J Salwe; S John Premendran; Bhawna B Shinde
Journal:  Pharmacognosy Res       Date:  2011-01

10.  Inhibition of toxic actions of phospholipase A2 isolated & characterized from the Indian Banded Krait (Bungarus fasciatus) venom by synthetic herbal compounds.

Authors:  Antony Gomes; Shamik Bhattacharya; Sanghamitra Mukherjee; Aparna Gomes
Journal:  Indian J Med Res       Date:  2012-07       Impact factor: 2.375
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