Literature DB >> 12686124

Structure and mechanism of soluble glucose dehydrogenase and other PQQ-dependent enzymes.

Arthur Oubrie1.   

Abstract

This paper discusses recent X-ray structures of several pyrroloquinoline quinone (PQQ)-dependent proteins in relation to their proposed modes of action. In addition, a detailed analysis of redox-related structural changes in the soluble PQQ-dependent glucose dehydrogenase is presented. A sequence comparison of that enzyme with a number of homologues shows that PQQ-dependent enzymes are much more widespread than has been assumed so far. In particular, the presence of a PQQ-dependent enzyme in at least one archaeon opens up the possibility that PQQ has been involved in prokaryotic metabolism since the early days of the evolution of bacterial life on earth.

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Year:  2003        PMID: 12686124     DOI: 10.1016/s1570-9639(03)00087-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  8 in total

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4.  Crystal structure of quinone-dependent alcohol dehydrogenase from Pseudogluconobacter saccharoketogenes. A versatile dehydrogenase oxidizing alcohols and carbohydrates.

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Review 5.  Quinone-Catalyzed Selective Oxidation of Organic Molecules.

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Journal:  Angew Chem Int Ed Engl       Date:  2015-11-04       Impact factor: 15.336

6.  Crystallization of quinoprotein glucose dehydrogenase variants and homologues by microseeding.

Authors:  Juan Sanchez-Weatherby; Stacey Southall; Arthur Oubrie
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-05-05

7.  Characterization of a novel PQQ-dependent quinohemoprotein pyranose dehydrogenase from Coprinopsis cinerea classified into auxiliary activities family 12 in carbohydrate-active enzymes.

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Journal:  PLoS One       Date:  2015-02-13       Impact factor: 3.240

Review 8.  Enzyme-Based Biosensors: Tackling Electron Transfer Issues.

Authors:  Paolo Bollella; Evgeny Katz
Journal:  Sensors (Basel)       Date:  2020-06-21       Impact factor: 3.576

  8 in total

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