Stress--where are we now? Does immunity play an intrinsic role?

The whole world experiences progress and development, however it is the human being who pays the price in stress--an inevitable part of modern life. When encountering stress, an individual reacts at the level of both the micro- and macroenvironment. Nowadays, stress is defined as a real or interpreted threat to the physiological or psychological integrity of an individual, which results in a physiological and/or behavioral response. In the article a review of the stress conceptualization, health consequences of stress (its neurophysiology and relation to autoimmune disease) as well as ways of management (exercises and psychotherapeutic intervention) is given.