Literature DB >> 12685

[Effects of naloxone on postoperative analgesia].

M N Abou-madi, S P Chin, J M Yaboub, H Keszler.   

Abstract

Two comparable groups of ten patients were studied. After nitrous oxide-oxygen fentanyl-pancuronium anesthesia, half the patients were reversed with a titrated dose of naloxone. Even in titrated doses naloxone rapidly abolished residual post-operative fentanyl analgesia in 80 p. 100 of the patients. In the control group none of the patients complained of pain for an average of six to eight hours. Blood gases in the recovery room were practically the same in reversed and non-reversed patients and were satisfactory.

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Year:  1976        PMID: 12685

Source DB:  PubMed          Journal:  Anesth Analg (Paris)        ISSN: 0003-3014


  3 in total

1.  Intrathecal delivery of a mutant micro-opioid receptor activated by naloxone as a possible antinociceptive paradigm.

Authors:  J H Kao; S L Chen; H I Ma; P Y Law; P L Tao; H H Loh
Journal:  J Pharmacol Exp Ther       Date:  2010-06-16       Impact factor: 4.030

2.  Methylnaltrexone: the evidence for its use in the management of opioid-induced constipation.

Authors:  Peter Deibert; Carola Xander; Hubert E Blum; Gerhild Becker
Journal:  Core Evid       Date:  2010-06-15

Review 3.  Search for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor.

Authors:  Pao-Luh Tao; Ping-Yee Law; Horace H Loh
Journal:  IUBMB Life       Date:  2010-02       Impact factor: 3.885

  3 in total

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