Literature DB >> 12684704

Susceptibility of HVS-immortalized lymphocytic HSC-F cells to various strains and mutants of HIV/SIV.

Mikako Fujita1, Akiko Yoshida, Akiko Sakurai, Junko Tatsuki, Fumiko Ueno, Hirofumi Akari, Akio Adachi.   

Abstract

Susceptibility of HSC-F, a cynomolgus macaque cell line immortalized by Herpesvirus saimiri, to infection with various primate immunodeficiency viruses were monitored. While NL432 clone of human immunodeficiency virus type 1 (HIV-1) did not grow at all in HSC-F cells, GH123 and GL-AN clones of HIV-2, and MA239 clone of simian immunodeficiency virus isolated from macaque monkeys (SIVMAC) did grow in these cells. In addition, NM-3 clone of a chimeric simian and human immunodeficiency virus (SHIV) grew fairly well in HSC-F cells. Mutational analyses of accessory genes of GL-AN were successfully performed in the HSC-F cells. These results have thus demonstrated the importance of this cell line for molecular biological studies on HIV/SIV.

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Year:  2003        PMID: 12684704

Source DB:  PubMed          Journal:  Int J Mol Med        ISSN: 1107-3756            Impact factor:   4.101


  9 in total

1.  A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.

Authors:  Emi E Nakayama; Hiroyuki Miyoshi; Yoshiyuki Nagai; Tatsuo Shioda
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

2.  A single amino acid of the human immunodeficiency virus type 2 capsid affects its replication in the presence of cynomolgus monkey and human TRIM5alphas.

Authors:  Haihan Song; Emi E Nakayama; Masaru Yokoyama; Hironori Sato; Jay A Levy; Tatsuo Shioda
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

3.  Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction.

Authors:  Ken Kono; Haihan Song; Masaru Yokoyama; Hironori Sato; Tatsuo Shioda; Emi E Nakayama
Journal:  Retrovirology       Date:  2010-09-08       Impact factor: 4.602

4.  Growth potentials of CCR5-tropic/CXCR4-tropic HIV-1mt clones in macaque cells.

Authors:  Naoya Doi; Ayaka Okubo; Mizumo Yamane; Yosuke Sakai; Akio Adachi; Masako Nomaguchi
Journal:  Front Microbiol       Date:  2013-07-29       Impact factor: 5.640

5.  Rhesus M1.3S Cells Suitable for Biological Evaluation of Macaque-Tropic HIV/SIV Clones.

Authors:  Naoya Doi; Sachi Fujiwara; Akio Adachi; Masako Nomaguchi
Journal:  Front Microbiol       Date:  2011-05-23       Impact factor: 5.640

6.  TRIM5α and Species Tropism of HIV/SIV.

Authors:  Emi E Nakayama; Tatsuo Shioda
Journal:  Front Microbiol       Date:  2012-01-24       Impact factor: 5.640

7.  Role of Human TRIM5α in Intrinsic Immunity.

Authors:  Emi E Nakayama; Tatsuo Shioda
Journal:  Front Microbiol       Date:  2012-03-15       Impact factor: 5.640

8.  Electrostatic potential of human immunodeficiency virus type 2 and rhesus macaque simian immunodeficiency virus capsid proteins.

Authors:  Katarzyna Bozek; Emi E Nakayama; Ken Kono; Tatsuo Shioda
Journal:  Front Microbiol       Date:  2012-06-05       Impact factor: 5.640

Review 9.  Impact of TRIM5α in vivo.

Authors:  Emi E Nakayama; Tatsuo Shioda
Journal:  AIDS       Date:  2015-09-10       Impact factor: 4.177

  9 in total

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