Literature DB >> 12682185

Distribution of the saa gene in strains of Shiga toxin-producing Escherichia coli of human and bovine origins.

Claire Jenkins1, Neil T Perry, Tom Cheasty, Darren J Shaw, Gad Frankel, Gordon Dougan, George J Gunn, Henry R Smith, Adrienne W Paton, James C Paton.   

Abstract

Certain strains of Shiga toxin-producing Escherichia coli (STEC) which do not have the locus of enterocyte effacement pathogenicity island carry the STEC autoagglutinating adhesin (saa) gene. The distribution of the saa gene in STEC isolates from patients with hemolytic-uremic syndrome (HUS), patients with less severe diarrheal disease, asymptomatic individuals, and healthy cattle was examined. saa-positive strains were detected more frequently (P < 0.001) in STEC strains from bovines (32 of 56 strains) than in those from humans (8 of 91 strains). No significant association (P = 0.135) was found between the saa gene and STEC isolated from patients with HUS (6 of 46 strains) or diarrhea (2 of 29 strains) and from healthy controls (0 of 16 strains).

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Year:  2003        PMID： 12682185      PMCID： PMC153935          DOI： 10.1128/JCM.41.4.1775-1778.2003

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


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