| Literature DB >> 12681409 |
Michael McHeyzer-Williams1, Louise McHeyzer-Williams, Joanne Panus, Rebecca Pogue-Caley, Gabriel Bikah, David Driver, Michael Eisenbraun.
Abstract
Helper T-cell-regulated B-cell responses constitute a major component of the immune response to many pathogens. Spatially and temporally organized cognate intercellular communication within secondary lymphoid organs is the critical regulating event in this complex adaptive response to antigen. Here, we discuss what is known of these molecular exchanges and their cellular consequences in a serial synapsis model of adaptive immunity.Mesh:
Substances:
Year: 2003 PMID: 12681409 DOI: 10.1016/s1286-4579(03)00012-1
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700