| Literature DB >> 1268088 |
R Rodvein, J N Lindon, P H Levine.
Abstract
Hydrogen peroxide in micromolar concentrations can induce shape change in human blood platelets, and can modify the aggregation and release reaction of these cells as induced by ADP or thrombin. In larger (millimolar) concentrations, H2O2 produces fusion of platelets with distortions in platelet morphology unlike those normally caused by aggregating agents. The production of H2O2 in vivo by granulocytes or other cells could influence the processes of haemostasis or thrombosis.Entities:
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Year: 1976 PMID： 1268088 DOI： 10.1111/j.1365-2141.1976.tb00968.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998