Literature DB >> 12680755

The binding potential between the cholera toxin B-oligomer and its receptor.

Xian-E Cai1, Jie Yang.   

Abstract

Employing atomic force microscopy as an in situ molecular force probe, we have measured the binding strength between cholera toxin B-pentamer (ctB) and its membrane receptor, ganglioside G(M1). By application of the basic principle of the reaction rate theory, key parameters of the ligand-receptor binding potential can be obtained from our data. The potential has a well with a spatial span of about 2.5 A and a depth of at least six times the thermal energy at room temperature. The very short range nature of the binding potential leads to the specificity of the ctB-G(M1) coupling.

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Year:  2003        PMID: 12680755     DOI: 10.1021/bi027016h

Source DB:  PubMed          Journal:  Biochemistry        ISSN: 0006-2960            Impact factor:   3.162


  10 in total

1.  Multi-step fibrinogen binding to the integrin (alpha)IIb(beta)3 detected using force spectroscopy.

Authors:  Rustem I Litvinov; Joel S Bennett; John W Weisel; Henry Shuman
Journal:  Biophys J       Date:  2005-07-22       Impact factor: 4.033

2.  GM1 clustering inhibits cholera toxin binding in supported phospholipid membranes.

Authors:  Jinjun Shi; Tinglu Yang; Sho Kataoka; Yanjie Zhang; Arnaldo J Diaz; Paul S Cremer
Journal:  J Am Chem Soc       Date:  2007-04-13       Impact factor: 15.419

3.  Plasma membranes are poised for activation of raft phase coalescence at physiological temperature.

Authors:  Daniel Lingwood; Jonas Ries; Petra Schwille; Kai Simons
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-09       Impact factor: 11.205

4.  High level expression of a functionally active cholera toxin B: rabies glycoprotein fusion protein in tobacco seeds.

Authors:  Siddharth Tiwari; Devesh K Mishra; Sribash Roy; Ankit Singh; P K Singh; Rakesh Tuli
Journal:  Plant Cell Rep       Date:  2009-10-10       Impact factor: 4.570

5.  Real-time full-spectral imaging and affinity measurements from 50 microfluidic channels using nanohole surface plasmon resonance.

Authors:  Si Hoon Lee; Nathan C Lindquist; Nathan J Wittenberg; Luke R Jordan; Sang-Hyun Oh
Journal:  Lab Chip       Date:  2012-10-21       Impact factor: 6.799

6.  Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes.

Authors:  A T Hammond; F A Heberle; T Baumgart; D Holowka; B Baird; G W Feigenson
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-25       Impact factor: 11.205

7.  Expression of toxin co-regulated pilus subunit A (TCPA) of Vibrio cholerae and its immunogenic epitopes fused to cholera toxin B subunit in transgenic tomato (Solanum lycopersicum).

Authors:  Manoj Kumar Sharma; Nirmal Kumar Singh; Dewal Jani; Rama Sisodia; M Thungapathra; J K Gautam; L S Meena; Yogendra Singh; Amit Ghosh; Akhilesh Kumar Tyagi; Arun Kumar Sharma
Journal:  Plant Cell Rep       Date:  2007-10-26       Impact factor: 4.570

8.  GM1 Softens POPC Membranes and Induces the Formation of Micron-Sized Domains.

Authors:  Nico Fricke; Rumiana Dimova
Journal:  Biophys J       Date:  2016-11-01       Impact factor: 4.033

9.  Dynamic response of HPV16/anti-HPV16 pairs with unbinding events studied by atomic force microscopy.

Authors:  Shiming Lin; Chung-Hung Hong; Bor-Ching Sheu; Long-Xin Wu; Wan-Chen Huang; Wei-Chih Huang; Cheng-Yan Guo
Journal:  Biochem Biophys Rep       Date:  2016-04-16

Review 10.  Plants as bioreactors for the production of vaccine antigens.

Authors:  Siddharth Tiwari; Praveen C Verma; Pradhyumna K Singh; Rakesh Tuli
Journal:  Biotechnol Adv       Date:  2009-04-06       Impact factor: 14.227

  10 in total

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