Literature DB >> 1268037

The reversibility by dipyridamole of the increased sensitivity of in vivo platelet aggregation in rabbits after alloxan.

A J Honour, T D Hockaday, J I Mann.   

Abstract

Rabbits hyperglycaemic after previous intravenous injection with alloxan show an increased sensitivity of the aggregation of platelets to adenosine diphosphate applied topically to injured arteries. This increased sensitivity is completely reversed by treatment with oral dipyridamole but returns if the dipyridamole is withdrawn.

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Year:  1976        PMID: 1268037      PMCID: PMC2041179     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  9 in total

1.  INFLUENCE OF A PYRIMIDOPYRIMIDINE DERIVATIVE ON DEAMINATION OF ADENOSINE BY BLOOD.

Authors:  R D BUNAG; C R DOUGLAS; S IMAI; R M BERNE
Journal:  Circ Res       Date:  1964-07       Impact factor: 17.367

2.  Experimental platelet embolism.

Authors:  A J HONOUR; R W RUSSELL
Journal:  Br J Exp Pathol       Date:  1962-08

3.  Morphology and enumeration of human blood platelets.

Authors:  G BRECHER; E P CRONKITE
Journal:  J Appl Physiol       Date:  1950-12       Impact factor: 3.531

4.  The fate of mural thrombi produced by injury in the ear artery of the rabbit.

Authors:  A J Honour; G W Pickering; B L Sheppard
Journal:  Br J Exp Pathol       Date:  1973-12

5.  Ultrastructure and behaviour of platelet thrombi in injured arteries.

Authors:  A J Honour; G W Pickering; B L Sheppard
Journal:  Br J Exp Pathol       Date:  1971-10

6.  Increased platelet aggregation responses to 5-hydroxytryptamine in patients taking chlorpromazine.

Authors:  D J Boullin; H F Woods; R P Grimes; D G Grahame-Smith
Journal:  Br J Clin Pharmacol       Date:  1975-02       Impact factor: 4.335

7.  Effect of a pyrimidopyrimidine derivative on thrombus formation in the rabbit.

Authors:  P R Emmons; M J Harrison; A J Honour; J R Mitchell
Journal:  Nature       Date:  1965-10-16       Impact factor: 49.962

8.  The variability of human platelet aggregation.

Authors:  M J Harrison; P R Emmons; J R Mitchell
Journal:  J Atheroscler Res       Date:  1967 Mar-Apr

9.  Increased sensitivity of in vivo platelet aggregation in rabbits after alloxan or streptozotocin.

Authors:  A J Honour; T D Hockaday
Journal:  Br J Exp Pathol       Date:  1976-02
  9 in total
  2 in total

1.  The synergistic effect of aspirin and dipyridamole upon platelet thrombi in living blood vessels.

Authors:  A J Honour; T D Hockaday; J I Mann
Journal:  Br J Exp Pathol       Date:  1977-06

2.  The effects of treatment with aspirin and an antithrombotic agent SH1117 upon platelet thrombus formation in living blood vessels.

Authors:  A J Honour; R D Carter; J I Mann
Journal:  Br J Exp Pathol       Date:  1977-10
  2 in total

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