Literature DB >> 12679814

Dax1 is required for testis determination.

Joshua J Meeks1, Jeffrey Weiss, J Larry Jameson.   

Abstract

The orphan nuclear receptor, Dax1, was originally proposed to act as an 'anti-testis' factor. We find, however, that Nr0b1 (also called Dax1 and Ahch, which encodes Dax1) is in fact required for testis differentiation.

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Year:  2003        PMID: 12679814     DOI: 10.1038/ng1141

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


  45 in total

1.  Two novel DAX1 gene mutations in Chinese patients with X-linked adrenal hypoplasia congenita: clinical, hormonal and genetic analysis.

Authors:  C M Wu; H B Zhang; Q Zhou; L Wan; J Jin; L Ni; Y J Pan; X Y Wu; L Y Ruan
Journal:  J Endocrinol Invest       Date:  2011-01-26       Impact factor: 4.256

2.  Sox3 is required for gonadal function, but not sex determination, in males and females.

Authors:  Jeffrey Weiss; Joshua J Meeks; Lisa Hurley; Gerald Raverot; Andrea Frassetto; J Larry Jameson
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272

Review 3.  The pathway to femaleness: current knowledge on embryonic development of the ovary.

Authors:  Humphrey Hung-Chang Yao
Journal:  Mol Cell Endocrinol       Date:  2005-01-31       Impact factor: 4.102

Review 4.  Genetic mechanisms underlying male sex determination in mammals.

Authors:  R P Piprek
Journal:  J Appl Genet       Date:  2009       Impact factor: 3.240

Review 5.  Hypogonadotropic hypogonadism in subjects with DAX1 mutations.

Authors:  Unmesh Jadhav; Rebecca M Harris; J Larry Jameson
Journal:  Mol Cell Endocrinol       Date:  2011-06-13       Impact factor: 4.102

6.  Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.

Authors:  Steven C Munger; David L Aylor; Haider Ali Syed; Paul M Magwene; David W Threadgill; Blanche Capel
Journal:  Genes Dev       Date:  2009-11-01       Impact factor: 11.361

7.  Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis.

Authors:  Bin Xu; Wei-Hsiung Yang; Isabelle Gerin; Chang-Deng Hu; Gary D Hammer; Ronald J Koenig
Journal:  Mol Cell Biol       Date:  2009-02-02       Impact factor: 4.272

8.  Human Y-chromosome variation and male dysfunction.

Authors:  Cláudia Márcia Benedetto de Carvalho; Fabrício Rodrigues Santos
Journal:  J Mol Genet Med       Date:  2005-12-06

9.  Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.

Authors:  Debora Bogani; Pam Siggers; Rachel Brixey; Nick Warr; Sarah Beddow; Jessica Edwards; Debbie Williams; Dagmar Wilhelm; Peter Koopman; Richard A Flavell; Hongbo Chi; Harry Ostrer; Sara Wells; Michael Cheeseman; Andy Greenfield
Journal:  PLoS Biol       Date:  2009-09-15       Impact factor: 8.029

10.  Gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish.

Authors:  Yi-Lin Yan; Thomas Desvignes; Ruth Bremiller; Catherine Wilson; Danielle Dillon; Samantha High; Bruce Draper; Charles Loren Buck; John Postlethwait
Journal:  Dev Dyn       Date:  2017-09-25       Impact factor: 3.780

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