OBJECTIVE: The objective of this study was to measure the relation between menstrual cycle length disorders and degree of obesity. METHODS: We enrolled 120 obese patients ages 18 to 40 y from an outpatient obesity clinic in a cross-sectional study. Patients with polycystic ovarian syndrome were excluded. Obesity was classified in five grades by relative weight. Waist-to-hip ratio was measured and comorbidities were assessed in each patient. Patients were asked to record menstrual cycle characteristics for 3 mo. Logistic regression analysis was performed, with age and type 2 diabetes as confounding variables. The patients' mean age was 29.9 +/- 6.4 y, the mean relative weight was 159.2 +/- 26.6%, and the mean waist-to-hip ratio was 0.84 +/- 0.1. RESULTS: Twenty-two (18.3%) patients had oligomenorrhea and 14 (11.7%) had amenorrhea. The risks for amenorrhea and oligomenorrhea were increased twofold by each unit increase of obesity grade. The odds ratio by waist-to-hip ratio tertile was not statistically significant. Type 2 diabetes and glucose intolerance were statistically significantly associated with amenorrhea and oligomenorrhea. CONCLUSIONS: Higher obesity grades were associated with higher probabilities of menstrual cycle disturbances such as amenorrhea and oligomenorrhea in this group of Mexican women.
OBJECTIVE: The objective of this study was to measure the relation between menstrual cycle length disorders and degree of obesity. METHODS: We enrolled 120 obesepatients ages 18 to 40 y from an outpatientobesity clinic in a cross-sectional study. Patients with polycystic ovarian syndrome were excluded. Obesity was classified in five grades by relative weight. Waist-to-hip ratio was measured and comorbidities were assessed in each patient. Patients were asked to record menstrual cycle characteristics for 3 mo. Logistic regression analysis was performed, with age and type 2 diabetes as confounding variables. The patients' mean age was 29.9 +/- 6.4 y, the mean relative weight was 159.2 +/- 26.6%, and the mean waist-to-hip ratio was 0.84 +/- 0.1. RESULTS: Twenty-two (18.3%) patients had oligomenorrhea and 14 (11.7%) had amenorrhea. The risks for amenorrhea and oligomenorrhea were increased twofold by each unit increase of obesity grade. The odds ratio by waist-to-hip ratio tertile was not statistically significant. Type 2 diabetes and glucose intolerance were statistically significantly associated with amenorrhea and oligomenorrhea. CONCLUSIONS: Higher obesity grades were associated with higher probabilities of menstrual cycle disturbances such as amenorrhea and oligomenorrhea in this group of Mexican women.
Authors: G Lambert-Messerlian; M B Roberts; S S Urlacher; J Ah-Ching; S Viali; M Urbanek; S T McGarvey Journal: Hum Reprod Date: 2011-06-15 Impact factor: 6.918
Authors: H Maredia; N L Hawley; G Lambert-Messerlian; U Fidow; M S Reupena; T Naseri; S T McGarvey Journal: Am J Hum Biol Date: 2018-04-16 Impact factor: 1.937
Authors: Annie E Newell-Fugate; Jessica N Taibl; Mouhamad Alloosh; Michael Sturek; Janice M Bahr; Romana A Nowak; Rebecca L Krisher Journal: PLoS One Date: 2015-06-05 Impact factor: 3.240
Authors: Sang Su Lee; Do Hoon Kim; Ga-Eun Nam; Hyo-Yun Nam; Young Eun Kim; Sung Ho Lee; Kyung Do Han; Yong Gyu Park Journal: Korean J Fam Med Date: 2016-01-27