Literature DB >> 12678805

Chemistry and biology of new marine alkaloids from the indole and annelated indole series.

Alparslan Aygün1, Ulf Pindur.   

Abstract

Chemistry and biology of marine natural products from the indole and annelated indole series have become an attractive research field for development of new pharmacological lead substances. In the past years some of the isolated natural organic compounds were synthesized by chemists and evaluated with great enthusiasm to find new lead natural compounds against different diseases. In this review the latest results for new compounds including isolation, biological evaluation, synthetic pathways and some retrosynthetic analyses are summarized.

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Year:  2003        PMID: 12678805     DOI: 10.2174/0929867033457511

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  7 in total

Review 1.  Marine indole alkaloids: potential new drug leads for the control of depression and anxiety.

Authors:  Anna J Kochanowska-Karamyan; Mark T Hamann
Journal:  Chem Rev       Date:  2010-08-11       Impact factor: 60.622

2.  Iridium-catalyzed regio- and enantioselective N-allylation of indoles.

Authors:  Levi M Stanley; John F Hartwig
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

3.  A simple copper-catalyzed two-step one-pot synthesis of indolo[1,2-a]quinazoline.

Authors:  Chunpu Li; Lei Zhang; Shuangjie Shu; Hong Liu
Journal:  Beilstein J Org Chem       Date:  2014-10-21       Impact factor: 2.883

4.  Camphorsulfonic Acid-Mediated One-Pot Tandem Consecutive via the Ugi Four-Component Reaction for the Synthesis of Functionalized Indole and 2-Quinolone Derivatives by Switching Solvents.

Authors:  Sivan Perumal Murugan; Hong-Jie Zhong; Chih-Yu Wu; Hao-Wei Pan; Chinpiao Chen; Gene-Hsian Lee
Journal:  ACS Omega       Date:  2022-02-10

Review 5.  Marine Indole Alkaloids.

Authors:  Natalie Netz; Till Opatz
Journal:  Mar Drugs       Date:  2015-08-06       Impact factor: 5.118

6.  Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives through copper-catalyzed intramolecular N-arylation.

Authors:  Fei Zhao; Lei Zhang; Hailong Liu; Shengbin Zhou; Hong Liu
Journal:  Beilstein J Org Chem       Date:  2013-11-14       Impact factor: 2.883

7.  A general synthesis of bis-indolylpiperazine-2,5-diones.

Authors:  Stephen Crooke; Christine Whitlock
Journal:  Molecules       Date:  2012-12-13       Impact factor: 4.411

  7 in total

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