Literature DB >> 12677537

Antibacterial evaluation of cnicin and some natural and semisynthetic analogues.

Maurizio Bruno, Sergio Rosselli, Antonella Maggio, Rosa Angela Raccuglia, Francesco Napolitano, Felice Senatore.   

Abstract

Some ester derivatives of salonitenolide have been prepared from cnicin, a germacranolide sesquiterpenoid. The compounds were tested for their antibacterial activity. The 8,15-diesters showed a good activity, comparable with that of cnicin. The 15-monoester compounds were not very active showing that esterification at the C-8 position is an important structural feature for antibacterial properties.

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Year:  2003        PMID: 12677537     DOI: 10.1055/s-2003-38491

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  3 in total

1.  Novel sesquiterpene lactone analogues as potent anti-breast cancer agents.

Authors:  Kyoko Nakagawa-Goto; Jo-Yu Chen; Yu-Ting Cheng; Wai-Leng Lee; Munehisa Takeya; Yohei Saito; Kuo-Hsiung Lee; Lie-Fen Shyur
Journal:  Mol Oncol       Date:  2016-03-25       Impact factor: 6.603

2.  Toward an integrated route to the vernonia allenes and related sesquiterpenoids.

Authors:  Da Xu; Michael A Drahl; Lawrence J Williams
Journal:  Beilstein J Org Chem       Date:  2011-07-05       Impact factor: 2.883

Review 3.  Natural and Synthetic Lactones Possessing Antitumor Activities.

Authors:  Younghoon Kim; Sandip Sengupta; Taebo Sim
Journal:  Int J Mol Sci       Date:  2021-01-21       Impact factor: 6.208

  3 in total

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